Chemical handling

Approximately 19 000 different chemical products are handled at approximately 150 workplaces within the university. You will find substances that affect people and the environment negatively as well as products that are basically harmless. Everyone who handles chemical products needs to have knowledge of the products' properties and how they should be handled. This page contains information that can help you find out how to handle chemicals correctly and safely.

Chemical Safety Officers

All departments/equivalent and campus areas that handle chemical products shall have one or more Chemcial safety officer. The Chemical Safety Officers are assigned by the Head of Department

Chemical Safety Officers

 

En man antecknar för att registrera kemikalier i dator

Chemical handling - information in different areas

Some chemical products can cause allergic reactions. It may be allergic skin reaction, astma symptoms or breathing difficulties. For an allergic reaction to occur you need to be exposed to an allergenic substance. It is important to avoid exposure to allergenic chemical products because if you get an allergy caused by exposure to an allergenic substance you can get symptoms from the handling of a very small amount of the substance.

For detailed information about allergenic chemical products, please go to section 37 a-g in the provision AFS 2011:19 Chemical hazards in the working environment.

Provision from Swedish work environment authority AFS 2011:19

Provision on medical examinations (only in Swedish) AFS 2019:3

 

If a risk assessment shows that there is a risk for exposure to any of the chemicals beneath, there are special requirements.

  • chemical products labelled with H317 (may cause allergic skin reaction) or H334 (may cause astma symptoms or breathing difficulties)
  • chemical products which contain ethyl- or methyl-2-cyanoacrylate
  • work that entails thermal degradation of materials that release iso-cyanates or processes that release formaldehyd

The documentation from the risk assessment should place particular emphasis on:

  • the areas and spaces where the hazardous chemical products shall be handled
  • the protective measures necessary to ensure that the exposure is as low as possible
  • which protective equipment to use and in which situations it is required
  • how the function of equipment and ventilation is to be checked and maintained to prevent allergenic substances from causing ill-health

If there is a risk for other employees to be exposed in the area where the substances are handled, signs must be posted. Also, those who are leading or are employed in the work with the substances mentioned above should be informed about how to carry out these tasks safely and about the risks involved with the handling.

Working with some of the allergenic chemical products require training, see section 37 e in the provision Chemical hazards in the working environment.

Read §37e in provision Chemical hazards in the working environment (AFS 2011:19)

Training is required both for those who lead the work or are employed in a work with chemical products if they are labelled with H317 or H334 due to the content of:

  • Diisocyanates.
  • Epoxy plastic components.
  • Organic acid anhydrides.
  • Formaldehyde resins.
  • Methacrylates.
  • Acrylates.

Training is also required for:

  • Work that involves thermal degradation that releases isocyanates.
  • Work with processes that release formaldehyde.

Work with the following substances that lasts longer than 30 minutes per week is also covered by training requirements:

  • Ethyl 2-cyanoacrylate.
  • Methyl 2-cyanoacrylate.

The training shall at the least contain information about the risks entailed by the work, and the protective measures that may need to be taken. A training certificate should be obtained and be no more than five years old. If a training certificate is missing, a sanction charge of SEK 10,000 per employee can be imposed by the Swedish Work Environment Authority.

Please, contact the Chemical Coordinator if you find out that you need a course.

annie.engstrom@uu.se

For some of the work with allergenic chemical products the employer must arrange for medical examination and some work require to do a medical examination with employability assessment, see section 37 f and g in the provision Chemical hazards in the working environment 2011:19. Also see the provision about Medical examinations (only in Swedish): Medicinska kontroller 2019:3.

The employer must arrange for medical examination for work where there is a risk of exposure to chemical products marked with H317 or H334 because they contain any of the following:

  • Epoxy plastic components.
  • Formaldehyde resins.
  • Methacrylates.
  • Acrylates.

Medical examination with employability assessment is required for those workers who are employed or will be employed in work that involves exposure to:

  • hazardous chemical products labeled with H334 because they contain
    • diisocyanates or ...
    • organic acid anhydrides
  • chemical products containing ethyl 2-cyanoacrylate or methyl 2-cyanoacrylate, if the work lasts more than 30 minutes per week,
  • work where isocyanates are released by thermal degradation.

If a medical exmination has not been carried out in cases where a employability assessment is required, a sanction charge may be imposed by the Swedish Work Environment Authority (for Uppsala University SEK 150,000).

Provision from Swedish work environment authority AFS 2011:19

Provision on medical examinations (only in Swedish) AFS 2019:3

Appointment for medical examination is booked with Uppsala University's occupational health service Falck.

Information including contact details to Falck

Flammable products is an umbrella term for flammable gases, flammable liquids and fire-reactive substances. Please go through the webbased course to achieve basic knowledge about the handling of flammable products. All handling of flammable products at the University should be done according to Procedure for tha handling of flammable products, UFV 2019/1840.

 

Uppsala University has permits to handle flammable products. The permits are administered by the chemical coordinator. The Vice-Chancellor is the permit holder for all of the University’s permits and has designated the relevant head of department/equivalent as the director for handling within his or her department/equivalent.

The permits are connected to the property, which effectively means that each campus area in which the University handles flammable goods has its own permit. Uppsala University must comply with the terms and conditions of the permit.

The permits that we have, with one exception, are valid until 2025-10-15. The terms and condition can be found in the Guidelines for handling of flammable products, see below.

A list of directors must be kept up to date and reported to the fire services/rescue services. The directors are the head of departments/equivalent and the chemical officers of each department. The list is administred by the Chemical Coordinator at the Unit for Environment and Physical Work Environment.

Major changes must be communicated to the campus manager at relevant campus and also to the chemical coordinator at the Unit for Environment and Physical Work Environement. Examples of changes to be reported are:

  • Change in quantity of flammable products
  • Relocation of flammable products
  • Changes in who are the directors at the department

For the handling of flammable products at Uppsala university there are risk analysis made for every campus, including classifcation plans.

According to the Act on Flammable and Explosive Goods (2010:1011), there must be an investigation into the risks of accidents and injuries that may affect life, health, the environment or property caused by fire or explosion as a result of handling flammable or explosive goods.

According to the regulation SRFVS 2004:7, an investigation must also be carried out where the risks of ignition of an explosive atmosphere are investigated and so-called classification plans drawn up.

Risk investigations and classification plans per campus areas (in Swedish)

Riskutredning och klassningsplan Biomedicinskt centrum Pdf, 179 kB.

Riskutredning och klassningsplan Ångströmlaboratoriet Pdf, 159 kB.

Riskutredning och klassninsgplan Rudbecklaboratoriet Pdf, 159 kB.

Riskutredning och klassningsplan Evolutionsbiologiskt centrum Pdf, 162 kB.

Riskutredning och klassningsplan Geocentrum Pdf, 149 kB.

Eachdepartment/equivalent must also carry out local risk assessments and handling routines must be in place. Support for producing these documents can be found in the property-wide risk investigation.

Classification plans

Bil 1 Fumehood with interlocked outlets Pdf, 41 kB.

Bil 2 Fumehoods without interlocked outlets Pdf, 40 kB.

Bil 3 Downdraft bench Pdf, 37 kB.

Bil 4 Storage cupboard Pdf, 36 kB.

Bil 5 Open tapping Pdf, 41 kB.

Bil 6 Gas central Pdf, 37 kB.

Bil 7 Gas flask Pdf, 37 kB.

Bil 8 Evolutionsmuseum display cases Pdf, 64 kB.

Fuel tank Botanical garden Pdf, 87 kB.

 

Specific requirements for CMR class products

The provisions Chemical Hazards in the Working Environment 2011:19 state that specific requirements apply when handling materials with the following hazard statements or risk phrases:

H350 May cause cancer
H340 May cause genetic defects
H360 May cause harm to fertility or to the unborn child

Investigation regarding the possibility of replacing a product

In order to handle CMR-classed products, a documented investigation must be carried out to show that it is not technically possible to replace the product with one that carries less risk of personal injury and harm. You can use linked form for the investigation. Save the signed form at the department, accessible in case it is requested.

Form for CMR-investigation Word, 110 kB.

Risk assessment

The risk assessment of CMR classed products shall clearly state where the CMR materials will be handled and what methods will be used to ensure that only necessary personnel are allowed in the area. Protective measures taken and any special personal safety equipment required to ensure minimal exposure must be specified. A description of how equipment, processes, and ventilation systems will be monitored to detect potentially dangerous anomalies must be included in the documentation.

Minimizing exposure

If closed handling is impossible, special measures must be taken in order to minimize exposure.

  • Choose a method that minimizes air contamination, spills, and splashing
  • Choose a process ventilation system capable of minimizing air contamination
  • Use protective clothing and gloves when at risk of contact with the material, and exchange them when commencing another type of work
  • Clean up spills quickly and safely
  • Clean surfaces daily and immediately following a completed task
  • Products and waste shall be stored and transported in shockproof, sealed, and clearly labelled containers

 

In accordance with the Swedish Work Environment Agency’s provisions Chemical Hazards in the Working Environment 2011:19 41§, the employer shall keep a register of employees who have been exposed to potential risks of ill-health while working with carcinogenic and mutagenic chemical products. The register must be kept for 40 years.

The chemical products concerned are those classified with one or several of the following hazard statements/risk phrases:

H350 May cause cancer
H340 May cause genetic defects

When should exposure be registered?
If it has been found that the level of exposure has been high enough to present a risk of ill-health in the form of cancer or genetic defects, the employer must register the exposed individuals. The exposure shall be able to be detected through the method of supervision decided upon.

Registration is mainly done whenever it is discovered that an employee has worked in an environment with higher levels of air contaminants than the occupational exposure limit value, if there is one for the material in question. It may also be necessary if an accident has resulted in a temporarily elevated level of exposure.

Causes of a high level of exposure include

  • inadequate ventilation
  • failure to use personal protective equipment for the work, or the inadequacy of such
  • failure to adhere to guidelines for handling and protection

If work has been carried out in violation of the provisions 40-44 §§, if planning and supervision of the work has been inadequate, or if employees have not been properly informed of the indications of the materials in question, there may also be cause to suspect increased risk of cancer or genetic defects. This also applies if the conditions for permits for the handling of A and B materials have not been fulfilled.

Routine
In order to ensure that this requirement is fulfilled at the University, the following routine must be adhered to:

  • the form "Register enligt AFS 2011:19" must be completed immediately following exposure. Heads of Department/equivalent are responsible for the completion of the form
  • The completed form is to be submitted to HR-avdelningen / Löneeneheten via the internal mail where the form is stored in the personal file of the employee.

Register according to AFS 2011:19

Chemicals covered by the Chemical Weapons Convention are export controlled according to either the regulations for war materials or the regulations for dual-use products. Dual-use products have, by definition, both civilian and military uses and are therefore common in civilian research. Pay particular attention to the export control regulations when chemicals must leave Uppsala University's premises, especially if they are to be transferred to another business or leave Sweden. Export control also regulates some research (technical information) on listed chemicals. This means that researchers sometimes need export permits in order to share regulated information with international partners.

Read more on Security and Safety Divisions page about export control

 

Export - flygplan och jordglob

Uppsala University handles a large number of chemical products, which vary in quantity, form and hazardousness. Those who are handling these products need to know about the risks associated with the various chemicals so that this is taken into account in decisions on how to store them.

 

Olika skåp för kemikalieförvaring

Chemical products must be stored in the right type of packaging intended for the product concerned, preferably in the original packaging if it is intended for storage. The packaging must be sealed and clean on the outside to prevent leakage and harm through skin contact. The packages must be labeles so that it is impossible to misunderstand what they contain or what risks are associated with the product. Read more on labeling in the University’s “Procedure for the Labelling of Chemical Products” UFV 2019/1706.

Chemical products may be stored in ventilated chemicals cupboards or chemical storerooms. The type of storage required is decided on a case-by-case basis. Flammable goods, for example, may require fire-retardant spaces if substantial quantities are stored.

It is important to take any combined effects into account when storing chemical products. For instance, it is inappropriate to store acids with bases, oxidising agents with oxidisable substances, or flammable substances with toxic substances.

Through procurements, Uppsala University has concluded agreements for purchase of chemicals. Orders should be made according to these agreements. The agreements can be found in the contract database from the Procurement and Purchase Office. Link on this page.

The purpose of Procedure for Purchase of Chemicals is to ensure that the quantities of chemicals bought are minimised, and that those that are purchased are intended for use in the University’s activities. This document is also intended as support for developing detailed routines for handling chemicals safely, from reception to waste management, in terms of health and accident risks and the environment.

If any aspects of the procurement procedure are unclear, contact the chemical coordinator at the unit for environment and physical work environment.

Contact the Procurement and Purchase Office if you have any questions about the procedure for ordering chemicals.

All purchases of chemicals must be done in accordance with current agreements. The agreements can be found in the framework agreement database.

If the University, for valid reasons, has to purchase hazardous chemicals outside of the agreement, the university shall avoid importing chemicals from non-EU/EEA countries. This is to prevent the university from becoming an importer. Hazardous chemicals are those chemicals which are classified as hazardous according to CLP legislation. Under the legislation, the university in the role of importer must, among other things, produce a safety data sheet and report data to the European Chemicals Agency ECHA.

Summary of import rules

Packaging, containers and pipelines containing chemical hazards shall be labeled so that you can identify the content and understand the risks associated with it.

All chemical products purchased after 1 June 2017 must be classified, labelled and packaged according to CLP. Chemical products classified and labelled according to the older system (orange hazard symbol) must be classified and labelled according to CLP. CLP is an abbreviation for Classification, Labelling and Packaging; an EU regulation.

Containers that have been filled with a chemical product for use in the laboratory may be labelled with name, hazard pictogram and hazard statement (eg flammable, carcinogenic).

Förpackning märkt med produktnamn, piktogram och faroangivelse

Visible pipelines which contain a hazardous chemical product shall be labelled with the information needed to clearly identify the contents and risks associated with this as well as an arrow indicating the direction of flow.

Labelling shall be positioned close to the most dangerous points, such as valves and joints, and at appropriate intervalls. Pipelines with gas under pressure (over 200kPa) shall also be labelled as written above even though the gas itself is harmless.

Employer who fails to label pipelines according to §20 (first part) in the provision AFS 2011:19 might be obligated to pay a sanction charge. Pipelines containing compressed air are excepted.

Read more in AFS 2011:19 §18 och §20 (Swedish)

Some chemicals, e.g. diethyl ether, tetrahydrofuran and 1,4-dioxane, can form explosive peroxides. Peroxide forming chemicals ar labelled with hazard statement EUH019.

The peroxides may form if the chemicals are subjected to light, heat or oxygen. Peroxide forming chemicals shall be kept away from light and heat. Opened bottles should not be kept for more than one year. Label bottles with date upon arrival and again when bottles are opened the first time.

Peroxidation can be detected using commercial test strips. If the content is cloudy, discoloured or crystallised the bottle shall not be opened, touched or moved because of risk for explosion. Contact the Chemical Coordinator at the Unit for Environment and Physical Work Environment for advise on handling.

Information about Diethyl Ether from Swedish Civil Contingencies Agency (Swedish)

Spillage of dangerous chemicals or infectious agent are potentially hazardous to human health and the environment and present an increased risk of accident if the leak is not immediately addressed and effectively disposed of in a safety-conscious manner.

Decontamination equipment

Any part of the University that handles chemicals must provide its own equipment for handling lesser spills. This equipment should include, for instance, absorption materials (such as vermiculite) and protective clothing. It is recommended to store decontamination equipment on a movable cart.

Decontamination of larger spills and spills of an unknown nature

When dealing with more extensive spills or when the type of spilled chemical is unknown, employees should refrain from decontaminating the spill themselves. Close the door to the room containing the spill and take measures to ensure that no unauthorized personnel enter, for instance by labelling the door.

Please contact RECOVER tel. 0771 - 10 35 00.

The number are manned 24 hours a day. English speaking personnel shall be available to handle calls. Provide as much information as possible on the materials to be decontaminated. If it is a chemical CAS number must be provided as well as information about a valid safety data sheet. If possible, show the risk assessment for the handling of the chemical to the contact person. The decontamination of the spill will be done based on the information you give.

Personnel shall be on-site and positioned to assist within two hours of a request. The company can also provide transportation of decontaminated materials.

Decontamination of equipment and furnishings

Decontamination of equipment or furnishings may be necessary e.g. when dispose of equipment or premises. Examples of equipment or furnishings are fume hoods, laboratory equipment, water traps, ventilation ducts and premises such as cabinets, benches and walls.

Contact RECOVER tel. 0771 - 10 35 00 and agree on the scope of the order. RECOVER must submit a certificate that decontamination has been carried out, unless otherwise agreed.

Incident or work injury

Any spillage that cause accidents, for instance skin injuries due to contact with the chemical in question, are to be reported as work injuries.

All other spills of harmful chemicals are considered incidents, i.e. an event that could have resulted in personal injury or an accident.

Work injuries and incidents shall be reported in the IA-system. Information via the link in the linklist.

Links related to decontamination

Här ska ändras till intern länk för tillbud/arbetsskada

Background

According to the Act 2014:799 and the Regulation 2014:880 on explosive precursors, professional users must report significant thefts and disappearances of products containing certain substances that can be used for the manufacture of home-made explosives, so-called explosive precursors.

Universities and colleges are regarded as professional users and the requirement therefore applies to these as well.

In general, it can be said that the higher the content of a particular substance is and the fewer other components that are present in a mixture, the more important it is that the product does not go astray.

See link at The Swedish Civil Contingencies Agency homepage (MSB).

The reporting requirement applies to a number of subjects listed on the linked page.

The reporting requirement applies to products that contain one of the substances. Exempted from the rules are products that contain at least five ingredients, and where the content of each constituent explosive precursor is lower than 1% by weight.

Some explosive precursors are subject to restrictions. Information about restrictions is gathered on a page that you find a link to on this page.

How we can prevent significant disappearances and thefts

  • Identify which of the above substances are in your stocks, including products in which they are included. It is possible to do a search in KLARA to find out which explosive precursors there are at the department/group.
  • Inform the staff in the group / unit that they need to be observant of the theft and disappearance of these and to whom they should report this.
  • Think about whether current substances and mixtures can be stored so that no unauthorized persons can access them, e.g. in locked spaces / cabinets.
  • Inventory regularly and log quantities so that deviations can be detected.
  • Limit purchased quantities.
  • Pay attention to suspicious behaviors in relation to these products.

 

Link to Swedish Civil Contingencies Agency and list of substances

Anyone who pursues an activity must avoid using chemical products that may involve risks to human health or the environment, if they can be replaced by products that are assumed to be less dangerous (The ‘substitution principle’, Chapter 2, Section 4 of the Swedish Environmental Code).

The University shall work on the substitution of any chemicals used that are dangerous to health and the environment. Naturally, substitutions will only be made where this can be done without jeopardising the quality of our research and education.

An alternative way to reduce the use of dangerous chemical products is to switch to a method or technology that is assumed to be less dangerous.

 

The National Substitution Group (NSG) is a national network of people from universities, county councils and regions, with the aim of helping to replace hazardous chemicals in research and education as well as health- and medical care.

Exchange list

The group's work on substitution has resulted in an substitution list that gives concrete proposals for substitutions of chemicals, handling routines and methods.

Review the list at your department and substitute your hazardous substances for the proposed alternative products. Each substitution has been successfully implemented in at least one of the network organisations. The list is continuously updated with new substitutions.

University participation

Uppsala University is represented in the group by the University's chemical coordinator. The group meets regularly to exchange experiences.

NSG's webpage. Here you find the substitution list both in Swedish and in English.

Has your department/equivalent implemented the use of a new chemical with less hazardous properties or a method that uses less amount of hazardous chemical?

Please, describe the substitution in an e-mail to the Chemical Coordinator at the Unit for Environment and Physical Work Environment. State which product you have substituted and in which handling. Specify if it is a substitution, change of method or phasing out. Describe the new handling with as much details as possible.

In this way the Chemical Coordinator can spread information about the substitution to others at the University and also in the National substitution group for chemical products (NSG).

In connection with the national environmental objective of a non-toxic environment, the Swedish Chemicals Agency has produced prioritisation lists for phase-out substances and risk reduction substances. These lists can help us in our work on substitution.

PRIO - KemI's tool for substitution. Phase-out and risk reduction substances.

At Uppsala university substances that require permits or are forbidden are sometimes needed. Various authorities with different legal requirements regulate the permits and exemptions. The university require special authoritiy for the buying of ethanol.

The University has permits to handle flammable products. The permits are administrated by the Chemical Coordinator at the Unit for Environment and Physical Work Environment.

Information about how to apply for permissions, special authority or exemptions:

 

For some of the cancirogenic, sensitizing or substances toxic to the reproduction a permit from the Swedish Work Environment Authorithy is required before handling the substances. When ordering such substances the supplier will ask about the permit before taking the order. The substances that requires permits are listed in Appendix 1 to the provision on Chemical Hazards in the Working Environment. The two groups of substances in appendix 1 are called A- and B-substances.

Chemical Hazards in the Working Environment 2011:19.

Group A

Substances from group A in the appendix may not be handled but there are some exceptions where a permit from the Swedish Work Environment Authority can be obtained. One exception could be researching a carcinogenic substance's effects. The same applies for chemical products which contain such a substance as contamination at a level of 0.1 weight per cent or more. All substances in group A are classified as cancirogenic.

Group B

Substances from group B may not be handled without permission from the Swedish Work Environment Authority. It also applies for products that contains such a substance at a level of 1 weight percent or more. The substances in group B are classified as cancirogenic, sensitizing or toxic to the reproduction.

Permit application

The application should be made by the department where the substance will be handled. The application shall be made in accordance to §49 in provision 2011:19 Chemical Hazards in the Working environment. Send the application to the Chemical coordinator at the division for Environment and Work Environment where it will be administrated and sent to the Swedish Work Environment Authority. The processing time for the application can be around three months. The authority might come for an inspection before a permission is given.

Some of the health hazardous substances require permission from the Public Health Agency of Sweden.

These are substances that due to their intrinsic properties can be dangerous to human life or health and can be used in order to get intoxicated or get other effects. The substances that need permission are listed in the appendix to regulation 1999:58

If your department needs a permit you should contact the Chemical Coordinator at the University who will then administrate the application. The application is done digitally. Name of product, intended use and estimated quantities must be reported in the application

The Public Health Agency of Sweden information information about permit for health hazardous substances (Swedish)

Exemptions

Permission is not required if the substances are used for reasearch and the following criteria is met:

  • The product is a mixture containing GBL and/or 1,4-butanediol
  • The product is prepared in a way so that GBL and/or 1,4-butanediol not easily can be used or extracted by methods that are easily applicable or economically advantageous

The excemptions are regulated in the provision 2014:3 - in Swedish

Section 9 of the Chemical Products (Handling, Import, and Export Prohibitions) Ordinance (1998:944) prohibits the use of mercury and chemicals containing mercury. The only general exception is the use of chemicals containing mercury for analytical purposes.

Chemical Products (Handling, Import, and Export Prohibitions) Ordinance (1998:944) - in Swedish

Application for exemption

In cases where the head of department/equivalent considers that the department/equivalent must continue to deal with chemicals containing mercury, it is possible to apply to the Swedish Chemicals Agency for an exemption.

To apply for an exemption, use the form from KemI:

Swedish Chemicals Agency form - in Swedish

Note that the application for exemption must be sent to the Chemical Coordinator at the Unit for Environment and Physical Work Environment, who will see to it that the application is registered and sent to the Swedish Chemicals Agency.

Further information about exemptions for mercury and chemicals containing mercury is available in the Swedish Chemicals Agency’s information.

Swedish regulations on mercury and articles containing mercury

To be able to purchase ethanol, a person must obtain authorisation from their head of department/equivalent. Fill in the form and send it to the Procurement and Purchase Office. The address is on the form. Ethanol can then be purchased via the University's eCommerce system Produktwebben.

Decision on the right to order ethanol and/or radionicleids (the form) Pdf, 399 kB.

The Public Health Agency of Sweden does not require a permit to be obtained for purchases of ethanol for scientific purposes. However, anyone purchasing industrial alcohol that is not completely denatured is required to keep records of purchases, use and stocks of alcohol. Reasons for differences between purchased quantity and consumed quantity must be identified, documented and measures must be taken. The documentation must be saved for at least two years.

Public Health Agency of Sweden information about technical spirit

Provision HSLF-FS 2022:63 on technical spirit (in Swedish).

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