Forskning vid Uppsala universitet

Forskningsprojekt från 2016-01-01 till 2019-12-31

The proposed project addresses the formation and function of the spinal locomotor network. This pattern generator operates as an autonomous metronome that creates a rhythmic output to the muscles as well ...

Forskningsprojekt från 2014-08-01 till 2015-07-30

Anmälan om utnyttjande av återvändarbidrag för beviljade postdoktorsstipendier inom medicin eller natur- och teknikvetenskap ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

Generation of architectural polarity impacts all cell types, ranging from epithelial cells to neurons and astrocytes, relates to tissue organization and links to disease development when misregulated. ...

Forskningsprojekt från 2011-01-01 till 2011-12-31

DEN PLANERADE KONFERENSENS NAMN OCH PLATS: Griboi och UppsalaTIDPUNKT FÖR KONFERENSEN: 10-12 maj, 2012 KORT MOTIVERING AV KONFERENSEN Sverige har år 2012 för första gången blivit utsett som värdland för ...

Forskningsprojekt från 2013-01-01 till 2016-12-31

The establishment of the musculoskeletal system of the head was tremendously important for the evolutionary transition from jawless to jawed vertebrates. The arrangement of cartilage, dermal bones, and ...

Forskningsprojekt från 2020-01-01 till 2023-12-31

The overall aim of the four projects included in this application is to discover novel pathways for the prevention of fractures in older people, a common problem in Sweden. The first project is intended ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

Knowledge of the evolutionary history of genes involved in developmental and physiological processes provides a foundation for understanding how specific genetic networks were established and how their ...

Forskningsprojekt från 2019-01-01 till 2022-12-31

Hip fractures annually affect almost 20,000 patients in Sweden. In about 2,000 patients with displaced femoral neck fractures insertion of a total hip arthroplasty (THA) is the best available treatment ...

Forskningsprojekt från 2020-01-01 till 2022-12-31

I Sverige drabbas varje år 70000 individer av en fragilitetsfraktur. Med en livstidstidsrisk om 50 % för kvinnor och 25 % hos män har Sverige en av de högsta förekomsterna i världen av dessa frakturer. ...

Forskningsprojekt från 2019-01-01 till 2021-12-31

Background and aimFemoral neck fractures (FNFs) are a great challenge for today´s healthcare and they are associated with high mortality and morbidity in the elderly. The treatment of displaced FNF has ...

Forskningsprojekt från 2015-07-01 till 2018-06-30

The origin of discrete paired and median fins with precisely defined shapes was a key innovation during the evolution of vertebrates, dramatically enhancing their locomotory abilities relative to their ...

Forskningsprojekt från 2014-01-01 till 2016-12-31

This project aims at studying the capacity of retinal progenitors to generate retinal neurons. We will explore the possibility to generate human retina in vitro based on induced pluripotent stem-cells ...

Forskningsprojekt från 2012-01-01 till 2014-12-31

Genetic control independent of sex hormones is important during the sexual differentiation of the brain. Some of these controllers might be encoded on the chromosome Y. The PI recently reported eleven ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

Vertebrates are animals of enormous ecological and economic importance. Their body plan has radiated into an astonishing range of morphologies and lifestyles, including our own. This project aims to undertake ...

Forskningsprojekt från 2012-01-01 till 2015-12-31

Osteoporotic fractures are common in Sweden. We don?t know why. The significance of lifestyle, comorbidity and genetic constitution on the risk of osteoporotic fractures is going to be examined in a cohort ...

Forskningsprojekt från 2016-07-01 till 2019-06-30

Chitin is an abundant biomolecule found in the exoskeletons of arthropods and the cell walls of fungi and certain bacteria. In vertebrates, unequivocal evidence of chitin was first reported in 2015 by ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

Tissues originate from progenitor cells that resemble each other on a molecular and morphological level. Progenitor cells make key decisions to change their identity and form divergent tissue types that ...

Forskningsprojekt från 2019-01-01 till 2021-12-31

Periprosthetic joint infections (PJI) and dislocations are serious early complications after total hip arthroplasty (THA), an operation that is almost as frequent as coronary percutaneous intervention. ...

Forskningsprojekt från 2016-01-01 till 2019-12-31

Fragility fractures are common in Sweden but we don’t know why. With increasing age, the importance of lifestyle seems to become more important than genetic constitution. The significance of diet, physical ...

Forskningsprojekt från 2012-01-01 till 2015-12-31

Endocytosis is an essential mechanism in all eukaryotes and functions in processes ranging from nutrient uptake to cell-cell signaling. Besides the classical signaling molecules, recent research has identified ...

Forskningsprojekt från 2014-01-01 till 2016-12-31

Granen, Picea abies, är mycket viktig både ekologiskt och ekonomiskt, och ger timmer till massa, papper, byggmaterial och biobränsle. Ved består av vattentransporterande xylemceller. I det här projektet ...

Forskningsprojekt från 2021-01-01 till 2024-12-31

How does neuronal activity translate into behaviour? We use the spinal locomotor network to study how circuits are coordinated to generate a variable output. Understanding how different movement patterns ...

Forskningsprojekt från 2015-01-01 till 2017-12-31

The EGF receptor family of receptor tyrosine kinases (EGFR, ErbB2-4) are key mediators of epithelial cell growth and survival and their over-activation contributes to the formation of a vast proportion ...

Forskningsprojekt från 2014-01-01 till 2019-12-31

Lymphatic system is composed of a hierarchy of vessels with specific features serving their unique functions: lymphatic capillaries that absorb interstitial fluid and collecting lymphatic vessels that ...