Forskning vid Uppsala universitet

Forskningsprojekt från 2021-01-01 till 2024-12-31

CRISPR-Cas-based adaptive immune systems are ubiquitous in bacteria and archaea. Paradoxically, CRISPR-associated endonucleases are remarkably slow at locating target DNA, with search times on the order ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

Antimicrobial resistance is a rapidly growing health concern but environmental aspects are largely understudied. Here, a 2017-2020 multi-disciplinary project is proposed in which development and transfer ...

Forskningsprojekt från 2014-01-01 till 2016-08-31

Kontaktberoende inhibiering av bakterietillväxt (CDI) är ett relativt nytt fynd där bakterier som innehar systemet kan stoppa tillväxten av andra bakterier som saknar systemet via cell-cell kontakt. CDI ...

Forskningsprojekt från 2021-01-01 till 2024-12-31

The function of microbial ecosystems is often dependent on symbiotic interactions between microbes. Such interactions are critical for essential biogeochemical processes such as global carbon, nitrogen ...

Forskningsprojekt från 2019-01-01 till 2022-12-31

Exceptionally well-preserved remains of a large theropod dinosaur have recently been found in Skåne. Outstanding details of the bones are visible with the naked eye but does that mean there is a potential ...

Forskningsprojekt från 2014-01-01 till 2018-12-31

Den eukaryota cellens ursprung representerar ett enigmatiskt, men svårlöst, evolutionärt pussel. Medan bevisen för att basen för eukaryota cellers ursprung grundar sig i en fusions-liknande modell är betydande ...

Forskningsprojekt från 2019-01-01 till 2021-12-31

Metamonads are a group of anaerobic eukaryotic microbes home to multiple parasites that infect hundreds of millions of people yearly and cause substantial economic damage. They feature a wide variety of ...

Forskningsprojekt från 2019-01-01 till 2022-12-31

Non-enveloped icosahedral dsRNA viruses that infect unicellular hosts are transmitted intracellularly. However, phylogenetically closely-related viruses found in multicellular hosts (metazoa) have acquired ...

Forskningsprojekt från 2016-07-01 till 2019-06-30

Background: A bacterial system to avoid spreading of phage in a bacterial population was recently discovered by the group of Prof. George Salmond, University of Cambridge, UK. This system is a toxin-antitoxin ...

Forskningsprojekt från 2018-01-01 till 2020-12-31

The project ’Nanowired bacteria’ aims to develop biocompatible nanostructured electrodes that can be used to penetrate the outer cell membrane of bacteria (e.g. Shewanella oneidensis). Intracellular protein ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

The world is facing an increasing difficulty to treat bacterial infections due to the emergence of antibiotic resistance. Meeting this challenge requires innovative approaches to reveal the complex mechanisms ...

Forskningsprojekt från 2017-01-01 till 2019-12-31

Antimicrobial resistance represents a significant source of morbidity and mortality. In this research program, I propose to use synthetic biology approaches to (1) develop novel biology devices for rapid ...

Forskningsprojekt från 2018-01-01 till 2019-06-30

The Arctic Ocean is particularly susceptible to ocean acidification (OA) compared to other oceans, as the cold surface water with relatively low salinity promotes high CO2 solubility. Sea-ice microorganisms ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

Globally we are surrounded by vast numbers of unknown microbes that are essential in Earth’s turnover of nutrients and geochemistry. Recently, diverse novel archaeal phylum-level lineages, characterized ...