Forskning vid Uppsala universitet

Forskningsprojekt från 2013-01-01 till 2015-12-31

Obtaining quantitative data from live cell images is the key to understanding molecular and cellular processes. Automated microscopes enable the collection of images at a rate which outpaces researchers ...

Forskningsprojekt från 2018-01-01 till 2020-12-31

The present project will meet the swedish national scientific, industrial and societal demands within high-quality material analysis by sustaining and advancing the role of the Tandem laboratory at Uppsala ...

Forskningsprojekt från 2014-01-01 till 2017-12-31

This project aims at investigating plant dynamics and forest development in the past (the last 130 000 years) and using this information to assist scientists modelling geographical range shifts in response ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

Generation of architectural polarity impacts all cell types, ranging from epithelial cells to neurons and astrocytes, relates to tissue organization and links to disease development when misregulated. ...

Forskningsprojekt från 2018-01-01 till 2021-12-31

Atmospheric rivers are long narrow bands of large integrated water vapor transport in the troposphere. At land fall they are usually associated with extreme conditions in terms of wind and precipitation ...

Forskningsprojekt från 2016-01-01 till 2018-12-31

We propose to study the structure-function relations of the bacterial ribosome. The ribosome is a large (2.5 MD) macromolecular complex that makes peptide chains with amino acid sequences as prescribed ...

Forskningsprojekt från 2012-01-01 till 2014-12-31

Ginseng polysaccharide is a complex mixture of neutral and acidic polysaccharides that has been proven to have anticancer activities. It functions through interactions with a protein called Galectin-3. ...

Forskningsprojekt från 2021-01-01 till 2023-12-31

Oxygen is essential for the health of lake ecosystems, but global climate warming may severely deplete oxygen concentrations by increasing microbial respiration rates and stifling atmospheric exchange. ...

Forskningsprojekt från 2019-01-01 till 2022-12-31

The main focus for this project is to understand hematopoiesis and neurogensis in crustaceans using the freshwater crayfish Pacifastacus leniusculus as a model animal. The hematopoietic tissue of crayfish ...

Forskningsprojekt från 2020-01-01 till 2022-12-31

För att effektivt fixera koldioxid kapslar cyanobakterier in Rubisco och karbonanhydras inuti en proteinorganell som kallas karboxysomen. Detta skapar en hög koncentration av koldioxid i närheten av Rubisco ...

Forskningsprojekt från 2016-01-01 till 2018-12-31

Bacterial infections are re-emerging as a serious health threat, caused by the rampant spread of resistance mechanisms towards clinically relevant antibiotics. Intestinal pathogens of the family enterobacteriaceae ...

Forskningsprojekt från 2020-01-01 till 2023-12-31

The rich archaeological and paleoenvironmental records from the Peloponnese peninsula (Greece) are investigated to provide an integrated understanding of the role of climate and climate change for Bronze ...

Forskningsprojekt från 2018-01-01 till 2021-12-31

Single cell analysis provides unprecedented opportunities to dissect and understand cells, the basic units of life. Until recently, there have been limited ways to study proteins in single cells in a high-throughput ...

Forskningsprojekt från 2013-01-01 till 2015-12-31

The origin of vertebrates was preceded by two dramatic genomic events, namely whole genome doublings or tetraploidizations. This generated numerous additional genes that have facilitated the evolution ...

Forskningsprojekt från 2021-01-01 till 2023-12-31

Currently there are no effective treatments that can cure metastatic breast cancer and therefore patients diagnosed with metastatic disease have an extremely poor prognosis. A critical program underlying ...

Forskningsprojekt från 2014-07-01 till 2017-06-30

Recent work shows that growth factor receptor signalling continues in endosomes, turning the endosomal network into a signalling platform. Different growth factors modulate the endosomal network and features ...

Forskningsprojekt från 2020-01-01 till 2022-12-31

Stora områden (20%) av svensk skogsmark har artificiellt dränerats genom dikning under de senaste århundradena för att öka produktionen av timmer. När dessa diken åldras, måste dikesrensning ofta utföras ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

Landscapes are multifaceted archives combining natural forming processes with cultural practises and land use strategies of past generations. The aim of the project is to explore the rich archives of the ...

Forskningsprojekt från 2016-01-01 till 2019-12-31

The Paleocene-Eocene Thermal Maximum (PETM), a period of global warming some 55 Ma, was triggered by multiple injections of isotopically light carbon into the atmosphere. Methane venting due to magma intrusion ...

Forskningsprojekt från 2019-01-01 till 2021-12-31

India’s agriculture, economy, water resources and societal well-being heavily rely on the Indian summer monsoon rainfall (ISMR). But ISMR is strongly influenced by the El-Nino Southern Oscillation (ENSO ...

Forskningsprojekt från 2020-12-01 till 2023-12-31

Assessing safety of early candidates in drug discovery is currently to a large extent based on animal studies, requiring large amounts of animals every year. The purpose of this project is to validate ...

Forskningsprojekt från 2016-01-01 till 2018-12-31

This project aims to develop a 3D-based differentiation method that can be customised for specific applications. Pluripotent stem cells (PSC) have great potential in regenerative medicine, disease modelling ...

Forskningsprojekt från 2012-01-01 till 2014-12-31

Current global warming, associated with the rapid release of CO2 by burning of fossil fuels, impacts ecosystems both on land and in the ocean, most notably in polar regions. Marine phytoplankton play a ...

Forskningsprojekt från 2019-01-01 till 2022-12-31

Deep sea sediment archives form the backbone of global palaeoclimate understanding. Such palaeoclimate reconstructions rest upon the geological law of superposition; sediment core layers become older with ...

Forskningsprojekt från 2020-01-01 till 2023-12-31

Learning and long-term memory (L&M) are complex phenomena and the relationships between specific memories and molecular events in neurons are still shrouded in mystery. Our approach to unravel L&M mechanisms ...

Forskningsprojekt från 2016-01-01 till 2016-12-31

The human genome is diploid, ie consists of a maternal and a paternal set of 23 homologous chromosomes with a unique nucleotide content. Phasing (haplotyping) refers to the assignment of the order of individual ...

Forskningsprojekt från 2019-01-01 till 2021-12-31

Målet med detta projekt är att studera toxicitetsmekanismer för miljöfarliga kemikalier via intelligent datagenerering med hjälp av ett automatiserat laboratorium som styrs av ett system med artificiell ...

Forskningsprojekt från 2019-01-01 till 2021-12-31

Extreme weather events, floods and droughts—problems that are likely to become more frequent and extreme due to climate change— inflict major losses and disproportionally affect lower income countries, ...

Forskningsprojekt från 2018-12-01 till 2022-11-30

Frågeställningarna i projektet är: I vilken utsträckning förändras förekomsten av extrema händelser och omfattningen av påverkan på kustzonen i ett ändrat klimat? Fokus är på stormar, översvämningar och ...

Forskningsprojekt från 2012-01-01 till 2014-12-31

I have recently identified over 40 novel genes that code for new members of the solute carrier family and many of these are likely to be novel transporters fro amino acids. We have unpublished data showing ...