Forskning vid Uppsala universitet

Forskningsprojekt från 2016-01-01 till 2019-12-31

A promising approach to treatment of disseminated cancer is a targeting, i.e. therapy based on specific recognition of cancer-associated molecular alteration in tumour cells. Success of the targeting therapy ...

Forskningsprojekt från 2019-01-01 till 2022-12-31

Antibiotic resistance is increasing at an alarming rate. There is consequently an urgent need for new approaches that can define efficient dosing strategies and facilitate development of treatments against ...

Forskningsprojekt från 2018-01-01 till 2020-12-31

The present project will meet the swedish national scientific, industrial and societal demands within high-quality material analysis by sustaining and advancing the role of the Tandem laboratory at Uppsala ...

Forskningsprojekt från 2014-01-01 till 2017-12-31

This project aims at investigating plant dynamics and forest development in the past (the last 130 000 years) and using this information to assist scientists modelling geographical range shifts in response ...

Forskningsprojekt från 2018-01-01 till 2021-12-31

Atmospheric rivers are long narrow bands of large integrated water vapor transport in the troposphere. At land fall they are usually associated with extreme conditions in terms of wind and precipitation ...

Forskningsprojekt från 2017-01-01 till 2019-12-31

This research plan describes a series of projects with an overall goal to elucidate how the amino acid transporters (SLCs) regulate neurotransmitter levels and energy metabolism in the brain.We usetransgenic ...

Forskningsprojekt från 2021-01-01 till 2023-12-31

Oxygen is essential for the health of lake ecosystems, but global climate warming may severely deplete oxygen concentrations by increasing microbial respiration rates and stifling atmospheric exchange. ...

Forskningsprojekt från 2014-01-01 till 2016-12-31

AIM: To understand molecular mechanisms regulating vascular abnormalization in glioblastoma and to identify vascular targets for cancer therapy. BACKGROUND: Glioblastoma are aggressive brain tumors characterized ...

Forskningsprojekt från 2020-01-01 till 2023-12-31

The rich archaeological and paleoenvironmental records from the Peloponnese peninsula (Greece) are investigated to provide an integrated understanding of the role of climate and climate change for Bronze ...

Forskningsprojekt från 2018-01-01 till 2027-12-31

The aim is to explore the relationship between genetic variation and biodiversity by combining genetic screens in non-model organisms (e.g. Atlantic herring and Darwin’s finches) with functional follow ...

Forskningsprojekt från 2020-01-01 till 2022-12-31

Stora områden (20%) av svensk skogsmark har artificiellt dränerats genom dikning under de senaste århundradena för att öka produktionen av timmer. När dessa diken åldras, måste dikesrensning ofta utföras ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

Landscapes are multifaceted archives combining natural forming processes with cultural practises and land use strategies of past generations. The aim of the project is to explore the rich archives of the ...

Forskningsprojekt från 2016-01-01 till 2019-12-31

The Paleocene-Eocene Thermal Maximum (PETM), a period of global warming some 55 Ma, was triggered by multiple injections of isotopically light carbon into the atmosphere. Methane venting due to magma intrusion ...

Forskningsprojekt från 2017-01-01 till 2017-12-31

The main mission of ELIXIR is to build a sustainable European infrastructure for biological information, supporting life-science research and its translation to society, the bio-industries, environment ...

Forskningsprojekt från 2020-01-01 till 2023-12-31

The purpose of the project is to investigate factors influencing targeted delivery of radionuclides using engineered scaffold proteins (ESP). The ultimate goal is to provide rationale for molecular design ...

Forskningsprojekt från 2019-01-01 till 2021-12-31

India’s agriculture, economy, water resources and societal well-being heavily rely on the Indian summer monsoon rainfall (ISMR). But ISMR is strongly influenced by the El-Nino Southern Oscillation (ENSO ...

Forskningsprojekt från 2012-01-01 till 2014-12-31

Current global warming, associated with the rapid release of CO2 by burning of fossil fuels, impacts ecosystems both on land and in the ocean, most notably in polar regions. Marine phytoplankton play a ...

Forskningsprojekt från 2015-01-01 till 2019-12-31

Sweden has a long and proud tradition in translational medicine, with major pharmaceutical and medical technology companies and many important Swedish research studies with large impact on clinical medicine ...

Forskningsprojekt från 2019-01-01 till 2022-12-31

Deep sea sediment archives form the backbone of global palaeoclimate understanding. Such palaeoclimate reconstructions rest upon the geological law of superposition; sediment core layers become older with ...

Forskningsprojekt från 2014-01-01 till 2016-12-31

Få mikroorganismer har så stor inverkan på människors och djurs hälsa som influensa A virus (IAV). IAV finns hos änder men korsar artbarriärer och infekterar tamfåglar, däggdjur och människa. Fågelvirus ...

Forskningsprojekt från 2019-01-01 till 2021-12-31

Extreme weather events, floods and droughts—problems that are likely to become more frequent and extreme due to climate change— inflict major losses and disproportionally affect lower income countries, ...

Forskningsprojekt från 2018-12-01 till 2022-11-30

Frågeställningarna i projektet är: I vilken utsträckning förändras förekomsten av extrema händelser och omfattningen av påverkan på kustzonen i ett ändrat klimat? Fokus är på stormar, översvämningar och ...

Forskningsprojekt från 2014-01-01 till 2016-12-31

The plant-derived molecule Thymoquinone (TQ) is promising against cancer and a drug candidate that has recently shown enhanced in vitro efficacy when formulated as nanoparticles (TQ-NPs) compared with ...

Forskningsprojekt från 2019-01-01 till 2021-12-31

In this proposal, we will implement a cross-disciplinary research program to target glioblastoma, the most common form of brain cancer. In the affected patient, a glioblastoma expands gradually through ...

Forskningsprojekt från 2014-01-01 till 2016-12-31

Lymphatic vasculature constitutes a network of vessels critical for the maintenance of tissue fluid homeostasis. Failure of the lymphatic system leads to chronic swelling, called lymphoedema, but it is ...

Forskningsprojekt från 2013-01-01 till 2017-12-31

This plan describes the continuation of a project, which has been ongoing in the PIs laboratory for the past ten years. The project started as a broad mapping of the glomerular transcriptome and has so ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

There are several forms of uncertainties in the predictive modeling of glacial mass balance. One of these uncertainties is to what degree melt water will refreeze, advect latent heat into, and stay as ...

Forskningsprojekt från 2021-01-01 till 2024-12-31

Glaciers outside the Greenland and Antarctic ice sheets are at present, despite their small volume (200,000 glaciers on Earth. A range of remote sensing and in situ observations of surface conditions and ...

Forskningsprojekt från 2012-01-01 till 2015-12-31

Heparan sulfate (HS) and the structurally related heparin occur in proteoglycan form at cell surfaces, in the extracellular matrix, and in intracellular vesicles. The heterogeneous polysaccharide chains ...

Forskningsprojekt från 2016-01-01 till 2018-12-31

Hydrologisk torka kan ha allvarliga konsekvenser för naturen och samhället, bland annat för jordbruk, vatten-/energiförsörjning och ekosystem. Klimatmodeller förutsäger att extrema händelser som den europatäckande ...