Forskning vid Uppsala universitet

Forskningsprojekt från 2016-01-01 till 2019-12-31

A promising approach to treatment of disseminated cancer is a targeting, i.e. therapy based on specific recognition of cancer-associated molecular alteration in tumour cells. Success of the targeting therapy ...

Forskningsprojekt från 2019-01-01 till 2022-12-31

Antibiotic resistance is increasing at an alarming rate. There is consequently an urgent need for new approaches that can define efficient dosing strategies and facilitate development of treatments against ...

Forskningsprojekt från 2012-01-01 till 2015-12-31

The proposed research is a multifaceted investigation centering on problems in homogeneous dynamics and fundamental questions about lattices. We will focus in particular on problems which hold the promise ...

Forskningsprojekt från 2017-01-01 till 2019-12-31

This research plan describes a series of projects with an overall goal to elucidate how the amino acid transporters (SLCs) regulate neurotransmitter levels and energy metabolism in the brain.We usetransgenic ...

Forskningsprojekt från 2014-01-01 till 2016-12-31

AIM: To understand molecular mechanisms regulating vascular abnormalization in glioblastoma and to identify vascular targets for cancer therapy. BACKGROUND: Glioblastoma are aggressive brain tumors characterized ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

The research program studies contact and symplectic topology and its relations to other geometric fields, in particular to physics inspired low-dimensional topology and knot theory. The main tool is theories ...

Forskningsprojekt från 2018-01-01 till 2027-12-31

The aim is to explore the relationship between genetic variation and biodiversity by combining genetic screens in non-model organisms (e.g. Atlantic herring and Darwin’s finches) with functional follow ...

Forskningsprojekt från 2017-01-01 till 2017-12-31

The main mission of ELIXIR is to build a sustainable European infrastructure for biological information, supporting life-science research and its translation to society, the bio-industries, environment ...

Forskningsprojekt från 2020-01-01 till 2023-12-31

The purpose of the project is to investigate factors influencing targeted delivery of radionuclides using engineered scaffold proteins (ESP). The ultimate goal is to provide rationale for molecular design ...

Forskningsprojekt från 2015-01-01 till 2019-12-31

Sweden has a long and proud tradition in translational medicine, with major pharmaceutical and medical technology companies and many important Swedish research studies with large impact on clinical medicine ...

Forskningsprojekt från 2014-01-01 till 2016-12-31

Få mikroorganismer har så stor inverkan på människors och djurs hälsa som influensa A virus (IAV). IAV finns hos änder men korsar artbarriärer och infekterar tamfåglar, däggdjur och människa. Fågelvirus ...

Forskningsprojekt från 2021-01-01 till 2024-12-31

The framework of string compactifications is of undisputed importance to connect string theory to the physics of our world, and has promoted progress in fields ranging from quantum gravity and cosmology ...

Forskningsprojekt från 2014-01-01 till 2016-12-31

The plant-derived molecule Thymoquinone (TQ) is promising against cancer and a drug candidate that has recently shown enhanced in vitro efficacy when formulated as nanoparticles (TQ-NPs) compared with ...

Forskningsprojekt från 2019-01-01 till 2021-12-31

In this proposal, we will implement a cross-disciplinary research program to target glioblastoma, the most common form of brain cancer. In the affected patient, a glioblastoma expands gradually through ...

Forskningsprojekt från 2021-01-01 till 2024-12-31

The Fukaya category is a powerful invariant of exact symplectic manifolds in the form of an A-infinity category, the objects of which consist of (a suitable class of) its Lagrangian submanifolds, while ...

Forskningsprojekt från 2014-01-01 till 2016-12-31

Lymphatic vasculature constitutes a network of vessels critical for the maintenance of tissue fluid homeostasis. Failure of the lymphatic system leads to chronic swelling, called lymphoedema, but it is ...

Forskningsprojekt från 2013-01-01 till 2017-12-31

This plan describes the continuation of a project, which has been ongoing in the PIs laboratory for the past ten years. The project started as a broad mapping of the glomerular transcriptome and has so ...

Forskningsprojekt från 2013-01-01 till 2016-12-31

This project studies the mathematical models arising from a variety of imaging techniques. These problems are formulated mathematically as "inverse problems" where one deduces information about the differential ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

Conserved quantities are important in various areas of physics, as in many cases they provide an essential characterization of a physical system. However, to define the mass, center of mass, angular and ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

This project is in the area of Theoretical and Mathematical Physics. The main emphasis is on the development of new geometrical ideas and concepts originating from the modern string theory and the quantum ...

Forskningsprojekt från 2012-01-01 till 2014-12-31

This project is in the area of Theoretical and Mathematical Physics. The main emphasis is on the development of new geometrical ideas and concepts originating from the modern string theory and ...

Forskningsprojekt från 2014-01-01 till 2016-12-31

During the past decade there has been an important development of the mathematical tools available for high-energy physics. I have participated in and contributed to this development of Generalized Complex ...

Forskningsprojekt från 2012-01-01 till 2015-12-31

Heparan sulfate (HS) and the structurally related heparin occur in proteoglycan form at cell surfaces, in the extracellular matrix, and in intracellular vesicles. The heterogeneous polysaccharide chains ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

This research project aims to study several related topics in higher dimensional Auslander-Reiten theory. Classical Auslander-Reiten theory is an important tool in representation theory of associative ...

Forskningsprojekt från 2013-01-01 till 2013-12-31

More than thirty years ago a result derived in the context of superspace supergravity indicated that even the most promising supergravity candidate had problems when viewed as a model for quantum gravity ...

Forskningsprojekt från 2017-01-01 till 2019-12-31

For over 40 years, natural products have served us well in combating cancer. The main sources of these successful compounds are microbes and plants from the nature. A major contribution comes from plant ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

Glioblastomas are highly aggressive brain tumors, characterized by microvascular proliferation and dysfunctional vessels. The abnormal vessels contribute substantially to patient mortality. Still, the ...

Forskningsprojekt från 2018-12-01 till 2021-12-31

The main purpose of this project is to further the understanding of exact Lagrangian manifolds in symplectic manifolds, and understand the relations to quantum physics. We propose the following specific ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

The lymph nodes provide a unique environment for immune activation and regulation, including antitumor responses. They arealso common sites for tumor metastasis. My own and others recent data has shownthat ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

This proposal aims at understanding molecular mechanisms of interspecies transmission of influenza A viruses (IAV) from the natural reservoir to poultry. Few viruses have affected humanity as much as IAV ...