Forskning vid Uppsala universitet

Forskningsprojekt från 2013-01-01 till 2016-12-31

The long-term goal of my research program is to unravel the functional link between soil fungal communities and nutrient and carbon cycling in terrestrial ecosystems. This is achieved by first establishing ...

Forskningsprojekt från 2013-01-01 till 2015-12-31

The ribosome is a large macromolecular complex of two subunits. It links amino acids into proteins according to the messenger RNA (mRNA) instructions. The twenty amino acids (aa) are covalently coupled ...

Forskningsprojekt från 2015-01-01 till 2017-12-31

Factors influencing body fat accumulation are poorly understood. Individuals that deposit fat in the liver, muscle and pancreas (ectopic fat) without increasing lean tissue (sarcopenic obesity) are prone ...

Forskningsprojekt från 2013-07-01 till 2016-06-30

The HIV/AIDS pandemic is still one of the most serious threats to human health, causing 1.7 million deaths in 2011 alone. Efforts to produce a vaccine to prevent HIV infection, which is needed to limit ...

Forskningsprojekt från 2014-01-01 till 2016-12-31

Det här unika tvärvetenskapliga projektet fokuserar på kardiovaskulära och metabola sjukdomar hos sällskapsdjur och deras ägare, genom att länka djur- och humandatabaser. Den planerade forskningen har ...

Forskningsprojekt från 2013-01-01 till 2017-12-31

Microorganisms drive biogeochemical processes and cycling of most biologically active elements in the biosphere. These ecosystem processes are critical for our long-term existence on earth, yet our knowledge ...

Forskningsprojekt från 2014-01-01 till 2017-12-31

This work aims to find strategies to prevent beta-cell death and restore beta-cell mass in Type 1 diabetes (T1D) in the absence of chronic immune suppression, i.e. to provide curative treatment. This project ...

Forskningsprojekt från 2013-01-01 till 2015-12-31

Over the past few years, new sequencing technologies have led to the discovery of novel types of RNA and novel catalytic functions for RNA in the cell. RNA-sequencing has further increased the ability ...

Forskningsprojekt från 2013-01-01 till 2016-12-31

The advent of massively parallel sequencing (MPS) has brought about significant changes genomics research. However, for use of MPS in genetic diagnostics, there are still many unsolved issues including ...

Forskningsprojekt från 2013-01-01 till 2015-12-31

This project - follow-up of the MINIMat trial - is implemented in Bangladesh, in a context, where food insecurity and maternal malnutrition still prevail, but where changing lifestyles and economic growth ...

Forskningsprojekt från 2011-01-01 till 2016-12-31

Diabeteskomplikationer - orsaker och förebyggande behandling ...

Forskningsprojekt från 2011-01-01 till 2016-12-31

Cardiovascular diseases are the most important complications of diabetes. Early identification and preventive treatment of persons at risk for diabetes complications are imperative. This research program ...

Forskningsprojekt från 2014-01-01 till 2016-12-31

Ända sedan människan påbörjade domesticeringen av våra husdjur och kulturväxter har man utnyttjat genetiken för att skapa raser och sorter med önskvärda egenskaper. Trots att domesticeringen, och senare ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

Type 1 diabetes (T1D) is in Sweden one of the most common chronic disorder in children, reaching more than 800 new patients per year (incidence doubled since 1990). Presently, diabetes can neither be prevented ...

Forskningsprojekt från 2013-01-01 till 2015-12-31

Archaea are present in all ecosystems as important facilitators of global cycling of nutrients. In the deep ocean they are as common as bacteria which make the archaea one of the most numerous groups of ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

Sex and recombination are ubiquitous in nature but evolutionary biologists struggle to explain their origins and evolution. Social insects have the highest recombination rates recorded in the animal kingdom ...

Forskningsprojekt från 2012-01-01 till 2015-12-31

Osteoporotic fractures are common in Sweden. We don?t know why. The significance of lifestyle, comorbidity and genetic constitution on the risk of osteoporotic fractures is going to be examined in a cohort ...

Forskningsprojekt från 2013-01-01 till 2016-12-31

The dog may have been the first animal to be domesticated and has since been an integral part of human culture. In spite of this, we have very little understanding of the genetic basis of traits separating ...

Forskningsprojekt från 2013-01-01 till 2016-12-31

Människan har under årtusenden bedrivit selektiv avel för prestationsegenskaper i häst, vilket över tid har resulterat i stora skillnader mellan individer för fenotyper såsom storlek, beteende, kroppsbyggnad ...

Forskningsprojekt från 2012-01-01 till 2015-12-31

While most feminist researchers today agree about the need to analyse both sex and gender there is a dearth of research on how sex and gender are interwoven. The purpose of this project is to develop theories ...

Forskningsprojekt från 2013-01-01 till 2018-12-31

Genetic variation forms the basic material that allows evolutionary change over time. Finding, describing and utilizing genetic variation to understand human history has long been a focus of evolutionary ...

Forskningsprojekt från 2014-01-01 till 2019-12-31

Kidney disease is a major cause for premature mortality in diabetic patients. The focus has recently shifted from a glomerulocentric to a predominantly tubulocentric view of mechanisms initiating the development ...

Forskningsprojekt från 2013-01-01 till 2015-12-31

The main purpose of the project is to develop and validate MRI and PET methods for studies of the obesity-diabetes-atherosclerosis disease process and its consequences with a currently funded PET-MR equipment ...

Forskningsprojekt från 2013-01-01 till 2017-12-31

Possibilities to prevent pancreatic beta-cell death and restore beta-cell numbers are crucial for optimal treatment of type 1 diabetes (T1D). Moreover, non-invasive monitoring of beta-cell mass would be ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

The aim of this project is to advance our knowledge of the origin and evolution of mitochondria using bioinformatic, ecological and experimental approaches. First, we will look into the past by applying ...

Forskningsprojekt från 2013-01-01 till 2016-12-31

Malfunction in cellular signaling is the cause of a wide variety of human diseases. Efficient and accurate flow of cellular information relies on scaffolding proteins that coordinate the physical assembly ...

Forskningsprojekt från 2015-01-01 till 2017-12-31

Regulatory RNAs control life processes in all organisms. Small bacterial antisense RNAs (sRNAs) act post-transcriptionally to regulate multitarget networks, complementing transcriptional control. This ...

Forskningsprojekt från 2013-01-01 till 2015-12-31

The specific objectives of the present studies are to clarify signal transduction pathways underlying pulsatile secretion insulin from beta cells and glucagon from alpha cells in the islets of Langerhans ...

Forskningsprojekt från 2013-01-01 till 2016-12-31

The present application focuses on the overall crosstalk during thromboinflammation in transplantation, which include the instant blood-mediated inflammatory reaction (IBMIR) in cell- and cell cluster-transplantation ...

Forskningsprojekt från 2013-01-01 till 2015-12-31

With described work we aim to clarify by which mechanisms amyloid harm cells and if amyloid can be prevented or resolved. Amyloid is cell-toxic aggregates and IAPP forms amyloid in beta-cells in type 2 ...