Forskning vid Uppsala universitet

Forskningsprojekt från 2016-07-01 till 2019-06-30

The overall aim is to understand platelet biogenesis, development and reactivity. The first two years of training will be in the host institute abroad, i.e., Framingham heart study (FHS), National Institutes ...

Forskningsprojekt från 2017-01-01 till 2022-12-31

Uppsala university has excelled in ribosome research over decades and already has a strong environment in the area of bacterial protein synthesis. We aim here at creating a novel type of ribosome research ...

Forskningsprojekt från 2016-01-01 till 2019-12-31

Over the next decades, dramatic increases of obesity and type 2 diabetes are expected in the U.S. and throughout the world. As insulin resistance is a usual intermediate step between obesity, type 2 diabetes ...

Forskningsprojekt från 2013-01-01 till 2017-12-31

Microorganisms drive biogeochemical processes and cycling of most biologically active elements in the biosphere. These ecosystem processes are critical for our long-term existence on earth, yet our knowledge ...

Forskningsprojekt från 2017-01-01 till 2017-12-31

The main mission of ELIXIR is to build a sustainable European infrastructure for biological information, supporting life-science research and its translation to society, the bio-industries, environment ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

Most of our timber producing trees are depending on a root associated symbiosis with fungi called ectomycorrhiza (ECM). ECM communities usually containing only a few stand forming trees but hundreds of ...

Forskningsprojekt från 2016-01-01 till 2018-12-31

Genetic recombination is central to evolution that serves as the unifying principle in the biology of higher organisms. This project will investigate how fine-scale recombination rate is controlled and ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

Sex and recombination are ubiquitous in nature but evolutionary biologists struggle to explain their origins and evolution. Social insects have the highest recombination rates recorded in the animal kingdom ...

Forskningsprojekt från 2016-01-01 till 2019-12-31

Influensa A-virus (IAV) utgör ett av de största hoten mot människor och andra djurs hälsa, trots tillgången till vaccin och antivirala läkemedel. En av de största utmaningarna är att kunna göra en förutsägelse ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

Animal cells maintain tissue function by secreting regulatory factors to signal their activity and nutrient status, pathogen infections or injury. These regulated vesicle fusion events are typically much ...

Forskningsprojekt från 2016-01-01 till 2019-12-31

Detailed stochastic models of single-cell molecular networks have led to important biological insights into diverse cellular phenomena, and computational experiments hold great promise to complement wet ...

Forskningsprojekt från 2017-01-01 till 2019-12-31

Projektet syftar till att förstå de genetiska grunderna för ekologiska anpassningar i humlor och hur de påverkas av klimatförändringar. Vi kommer att sekvensera genomen hos två alpina humlearter med modern ...

Forskningsprojekt från 2016-07-01 till 2019-06-30

Chitin is an abundant biomolecule found in the exoskeletons of arthropods and the cell walls of fungi and certain bacteria. In vertebrates, unequivocal evidence of chitin was first reported in 2015 by ...

Forskningsprojekt från 2016-01-01 till 2019-12-31

The origin of the eukaryotic cell remains one of the most enigmatic and contentious puzzles in modern biology. The few pieces of this puzzle that have been identified thus far indicate that the eukaryotic ...

Forskningsprojekt från 2013-01-01 till 2018-12-31

Genetic variation forms the basic material that allows evolutionary change over time. Finding, describing and utilizing genetic variation to understand human history has long been a focus of evolutionary ...

Forskningsprojekt från 2016-01-01 till 2018-12-31

The overall aim of this program is to better understand the co-evolution among retroviruses and hosts, as well as the effects of endogenous retroviruses (ERVs) on host biology. All retroviruses must become ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

The current era of genomics has made whole-genome sequencing widely available. However, the structurally complex parts of most genomes – centromeres, telomeres, and large transposable elements (TEs) – ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

The aim of this project is to advance our knowledge of the origin and evolution of mitochondria using bioinformatic, ecological and experimental approaches. First, we will look into the past by applying ...

Forskningsprojekt från 2016-01-01 till 2018-12-31

Mikroorganismer bildar ofta komplexa samhällen i jord och vatten, men även inuti växter och djur, antingen som parasiter eller som positiva symbionter. RNA-sekvensering utgör en kostnadseffektiv möjlighet ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

We will elucidate fundamental question regarding protein-protein interactions involving Short Linear Motifs (SLiMs) through investigation of their prevalence, function, cooperativity, regulation and deregulation ...

Forskningsprojekt från 2016-04-01 till 2017-12-31

NBIS is a continuation of BILS (Bioinformatics Infrastructure for Life Sciences) now also including WABI (Wallenberg Advanced Bioinformatics Infrastr.), SILS (Systems Biology Infrastr. for Life Sciences ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

The world is facing an increasing difficulty to treat bacterial infections due to the emergence of antibiotic resistance. Meeting this challenge requires innovative approaches to reveal the complex mechanisms ...

Forskningsprojekt från 2015-01-01 till 2017-12-31

Regulatory RNAs control life processes in all organisms. Small bacterial antisense RNAs (sRNAs) act post-transcriptionally to regulate multitarget networks, complementing transcriptional control. This ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

Although not a new idea, recent studies suggest that differences in the composition of symbiotic microbes between hosts could lead to reproductive isolation, and as a consequence speciation. Despite the ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

Globally we are surrounded by vast numbers of unknown microbes that are essential in Earth’s turnover of nutrients and geochemistry. Recently, diverse novel archaeal phylum-level lineages, characterized ...