Forskning vid Uppsala universitet

Forskningsprojekt från 2019-01-01 till 2024-12-31

A new generation of superluminous X-ray free-electron lasers (XFEL) will deliver billions of exposures per day at intensities up to 100-times higher than intensities available from existing XFELs. The ...

Forskningsprojekt från 2013-01-01 till 2013-12-31

With this application we seek for the funds to invite world-leading experts as keynote speakers to the 11th International Conference on Low Energy Antiproton Physics (LEAP2013). This biennial event has ...

Forskningsprojekt från 2016-01-01 till 2019-12-31

Resonant inelastic soft X-ray scattering spectroscopy has several important features that makes is attractive for studies ranging from fundamental phenomena in atoms and molecules to the function of complex ...

Forskningsprojekt från 2011-01-01 till 2013-12-31

With 70-90% of the new drug-like molecules synthesised at date showing poor water solubility computational tools that allow predictions of the solubility and give suggestions on how to improve this property ...

Forskningsprojekt från 2012-01-01 till 2013-12-31

The field of chemical safety predictions aims at establishing the safety of novel chemical structures in silico, using computational models based on existing in vitro and in vivo data. The field is hampered ...

Forskningsprojekt från 2012-07-01 till 2015-06-30

The aim of the proposed project is to study the magnetism of a new family of singlemolecule magnets (SMMs), and determine how their magnetic properties are modified when interacting with the surface of ...

Forskningsprojekt från 2019-01-01 till 2022-12-31

Antibiotic resistance is increasing at an alarming rate. There is consequently an urgent need for new approaches that can define efficient dosing strategies and facilitate development of treatments against ...

Forskningsprojekt från 2019-01-01 till 2022-12-31

The vast majority of modern pharmacologically active compounds demands advanced drug delivery systems (ADDSs) to be developed as orally administered medicines. The goal for this project is to design lab ...

Forskningsprojekt från 2019-01-01 till 2021-12-31

Most molecules have limited ability to cross the blood-brain barrier (BBB), heavily restricting the future expansion of neurotherapeutics development. With the current proposal, we aim to evaluate the ...

Forskningsprojekt från 2016-11-01 till 2016-11-30

Name of the conference: Current Trends in Multifunctional Dirac Materials, an International Workshop. In Swedish: Aktuella trender i  multifunktionella Dirac materialer, en internationel workshop.The ...

Forskningsprojekt från 2021-01-01 till 2024-12-31

The purpose of this project is to push the limits for oral drug delivery and disposition with the use of breakthrough methodologies and models for accurate and precise prediction of oral drug delivery ...

Forskningsprojekt från 2011-01-01 till 2015-10-31

Ansökan Swedish in-kind contribution to XFEL ...

Forskningsprojekt från 2017-01-01 till 2020-12-31

The measurement of stellar chemical abundancesis a fundamental problem in astrophysics. While spectral lines are routinely measured at accuracies of 1%, systematic errors dominate interpretation and errors ...

Forskningsprojekt från 2015-01-01 till 2017-12-31

Detta projekt söker ny kunskap om tidigmodern farmaci genom att rekonstruera försvunna farmaceutiska färdigheter rörande handel med, samt hantering och komposition av mediciner. Varifrån kom substanserna ...

Forskningsprojekt från 2013-01-01 till 2016-12-31

X-ray Free Electron lasers push the frontier of science with their extremely short and brilliant pulses. The high X-ray intensities allow new ways to image single bio-particles in their native environment ...

Forskningsprojekt från 2019-01-01 till 2022-12-31

To understand the complex biochemical interactions between drugs and their targets, it is necessary to identify the molecular entities involved and determine their abundance and spatial distribution in ...

Forskningsprojekt från 2013-01-01 till 2015-12-31

Recent data from our lab suggest that L-DOPA-induced dyskinesia (LID) in Parkinson´s disease (PD) is associated with abnormal opioid peptide metabolism in the striatum, but not in the projection target ...

Forskningsprojekt från 2019-01-01 till 2022-12-31

Cardiovascular disease (CV) contributes greatly to high mortality and morbidity in diabetes and thus, treatment focuses on controlling risk factors, e.g. hypertension, hyperlipidemia and obesity. However ...

Forskningsprojekt från 2021-01-01 till 2024-12-31

A key insight from quantum mechanics is the importance of processes involving electron rearrangement, such as charge transfer (CT) in collisions between atoms. In dilute plasmas such as those often observed ...

Forskningsprojekt från 2014-01-01 till 2017-12-31

Recent progresses with manipulating electron beam in transmission electron microscopes opened new frontiers of research. Use of the electron vortex beams, that is beams that carry an orbital angular momentum ...

Forskningsprojekt från 2020-01-01 till 2023-12-31

Emergent phenomena, such as insulator to metal transitions, magnetism and superconductivity, often occur in materials where many degrees of freedom are strongly coupled to each other. To understand, and ...

Forskningsprojekt från 2019-01-01 till 2022-12-31

The aim of this project is to develop mathematical models, methods and processes that will allow data from composite assessments of patient status to be efficiently utilized with the purpose of improving ...

Forskningsprojekt från 2020-01-01 till 2022-12-31

We hypothesize that alterations in the epigenome in response to adverse events and / or alcohol binging in early life may be a critical factor contributing to risk and resilience to alcohol use disorders ...

Forskningsprojekt från 2015-12-01 till 2018-11-30

The CO-ACTION project aims to develop and provide a framework for evaluating and validating the effectiveness of antibiotic (AB)- and non-antibiotic (NA) combinations (COMs) in the preclinical setting ...

Forskningsprojekt från 2014-08-01 till 2018-07-31

The overall aim of this PhD project is to develop and implement state-of-the-art targeted and global proteomic technologies to understand the role of active processes mediated by transporter proteins and ...

Forskningsprojekt från 2011-01-01 till 2013-12-31

Peptides and proteins are objects of great interest as potential new medicines for the treatment of central nervous system (CNS) disorders. However, the transport into the brain is minute due to the blood-brain ...

Forskningsprojekt från 2019-07-01 till 2022-06-30

The proposed research aims to develop a new physico-chemical investigation technique able to detect intermediates of electrocatalytic reactions. Electrochemical Induced Raman Spectroscopy, couples electrochemistry ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

The project is aimed to develop a sensitive chemical sensor based on a microfabricated diamond waveguide. By coupling mid-IR light into a macroscopic diamond crystal FTIR-ATR spectroscopy can be performed ...

Forskningsprojekt från 2012-01-01 till 2013-12-31

We will develop a space and time-dependent Green function formalism that can be used to address questions concerning correlation and scattering effects on a nanoscale in modern materials. As most measurements ...

Forskningsprojekt från 2011-01-01 till 2013-12-31

Cancer is a major public health issue globally and about 25% of all deaths in the EU and USA are due to cancer. Liver cancer, the fifth most common tumor, is often offered a palliative treatment with chemotherapeutic ...