Forskning vid Uppsala universitet

Forskningsprojekt från 2015-01-01 till 2018-12-31

Generation of architectural polarity impacts all cell types, ranging from epithelial cells to neurons and astrocytes, relates to tissue organization and links to disease development when misregulated. ...

Forskningsprojekt från 2015-11-09 till 2016-07-09

Syfte och mål: Målet med detta projekt är att utreda möjligheten att utveckla en autonom termisk brytare. Det långsiktiga målet är att APR Technologies AB skall kunna tillverka och sälja denna komponent ...

Forskningsprojekt från 2016-01-01 till 2018-12-31

We propose to study the structure-function relations of the bacterial ribosome. The ribosome is a large (2.5 MD) macromolecular complex that makes peptide chains with amino acid sequences as prescribed ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

This project concerns computational methods for wave propagation problems. We propose to develop efficient and accurate techniques to implement important boundary and/or interface conditions for second ...

Forskningsprojekt från 2016-01-01 till 2018-12-31

Bacterial infections are re-emerging as a serious health threat, caused by the rampant spread of resistance mechanisms towards clinically relevant antibiotics. Intestinal pathogens of the family enterobacteriaceae ...

Forskningsprojekt från 2014-07-01 till 2016-12-31

Syfte och mål: Sverige har flera stora grupperingar med världsledande forskning kring nya tekniker för omvandling av solenergi till el eller direkt till bränslen. Det finns också svenska företag och institut ...

Forskningsprojekt från 2014-07-01 till 2017-06-30

Recent work shows that growth factor receptor signalling continues in endosomes, turning the endosomal network into a signalling platform. Different growth factors modulate the endosomal network and features ...

Forskningsprojekt från 2016-01-01 till 2019-12-31

We aim to study molecule-surface interactions and shallow trap states on single crystal semiconducting metal oxides and thin solid film metal oxides by two main methods: infrared reflection-absorption ...

Forskningsprojekt från 2016-01-01 till 2018-12-31

This project aims to develop a 3D-based differentiation method that can be customised for specific applications. Pluripotent stem cells (PSC) have great potential in regenerative medicine, disease modelling ...

Forskningsprojekt från 2016-01-01 till 2016-12-31

The human genome is diploid, ie consists of a maternal and a paternal set of 23 homologous chromosomes with a unique nucleotide content. Phasing (haplotyping) refers to the assignment of the order of individual ...

Forskningsprojekt från 2014-01-01 till 2016-12-31

Lymphatic vasculature constitutes a network of vessels critical for the maintenance of tissue fluid homeostasis. Failure of the lymphatic system leads to chronic swelling, called lymphoedema, but it is ...

Forskningsprojekt från 2011-04-01 till 2017-03-31

I have recently identified over 40 novel genes that code for new members of the solute carrier family and many of these are likely to be novel transporters fro amino acids. My research group are currently ...

Forskningsprojekt från 2014-01-01 till 2017-12-31

Biological imaging using Free-Electron Laser (FEL) pulses has in the last two years manifested its great potential. In summary we have demonstrated: i) That it is possible to get high quality atomic resolution ...

Forskningsprojekt från 2014-01-01 till 2017-12-31

Understanding the key forces underlying population differentiation and speciation, the forces that ultimately generate biodiversity, is a fundamental question in evolutionary biology. To address this question ...

Forskningsprojekt från 2014-01-01 till 2017-12-31

The insight that quantum holonomies, i.e., non-Abelian geometric phases, have an inherent resilience to errors has opened up a path to overcome unwanted open system effects and parameter instabilities ...

Forskningsprojekt från 2013-01-01 till 2016-12-31

Melanization is caused by activation of the Prophenoloxidase activating system ( ProPO ) which consists of a proteolytic enzyme cascade and prophenoloxidase. When activated the ProPO-system generates several ...

Forskningsprojekt från 2015-01-01 till 2017-12-31

This research proposal focuses on the biology of mast cells and their progenitors in allergic asthma and respiratory infections. Our data show that the number of mast cell progenitors increase in the lung ...

Forskningsprojekt från 2015-01-01 till 2017-12-31

The EGF receptor family of receptor tyrosine kinases (EGFR, ErbB2-4) are key mediators of epithelial cell growth and survival and their over-activation contributes to the formation of a vast proportion ...

Forskningsprojekt från 2016-01-01 till 2019-12-31

Direct physical contacts between cellular organelles constitute reaction centers in cells where rapid and specific transfer of ions, lipids and metabolites are thought to occur. Both organelles and contacts ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

Resonant Inelastic Soft X-ray Scattering (RIXS) and related experiments are applied to atoms, molecules, liquids and molecular materials. The most important assets of the RIXS process include Ångström-scale ...

Forskningsprojekt från 2014-01-01 till 2017-12-31

The aim of this project is to understand the different functions of small RNAs - in the developing organism and as a defense system against pathogenic bacteria.Small RNAs are important regulators of most ...