Forskning vid Uppsala universitet

• Hälsa och vård innan konception

  Forskningsprojekt från 2015-07-01 till 2015-07-31

  Preconception Health and Care International Conference, Uppsala 2016-02-17, 18 and 19Preconception care is defined as a set of interventions that aim to identify and modify biomedical behavioural and ...

• Torrent framåt: Algoritmer för röntgenlasrar för att studera struktur, funktion och dynamik

  Forskningsprojekt från 2019-01-01 till 2024-12-31

  A new generation of superluminous X-ray free-electron lasers (XFEL) will deliver billions of exposures per day at intensities up to 100-times higher than intensities available from existing XFELs. The ...

• 21:e Svenska Konferensen om Makromolekylers Struktur och Funktion

  Forskningsprojekt från 2016-11-01 till 2016-11-30

  The 21th Swedish Conference on Macromolecular Structure & Function.Tällberg, June 16-19, 2016Structural biology, Biochemistry, Biophysics & Molecular Biology are strong areas in Swedish research. The Swedish ...

• En singelmolekyl-fälla av DNA origami för att studera självskapade värmechocker hos enzym

  Forskningsprojekt från 2017-07-01 till 2020-06-30

  In this proposal, we aim to explore the uncharted interactions between the heat released from an exothermic enzymatic reaction, and the enzyme’s structure and function. To achieve this goal, we chose pyruvate ...

• En Fundamental Ansatts till Laddningsöverföring i Endimensionella Koordinationspolymerer

  Forskningsprojekt från 2019-01-01 till 2022-12-31

  Charge transporting materials play a cruical role in one of the most active research areas: the development of molecular materials to facilitate the conversion of solar energy into electricity, fuels and ...

• Ett tveeggad svärd? Kvantitativ undersökning av avvägningar i CRISPR immunförsvar

  Forskningsprojekt från 2021-01-01 till 2024-12-31

  CRISPR-Cas-based adaptive immune systems are ubiquitous in bacteria and archaea. Paradoxically, CRISPR-associated endonucleases are remarkably slow at locating target DNA, with search times on the order ...

• Mekanismen bakom replikationsinitiering - En genom-sökning

  Forskningsprojekt från 2018-12-01 till 2021-12-31

  At the core of this project is the question how a cell coordinates growth with DNA replication. We have recently shown that the bacterium E. coli does this by triggering replication initiation at a fixed ...

• En avancerad immunologisk metod för att karakterisera terapeutiska antikroppar med hjälp av en liten mängd humant blod

  Forskningsprojekt från 2013-01-01 till 2014-12-31

  This project aims to develop of a novel human ex-vivo whole blood loop system for an improved characterization of therapeutic antibodies in order to avoid irrelevant and unnecessary animal studies. Today ...

• Avancerade nanostrukturerade material för effektiv PEM-bränsleceller

  Forskningsprojekt från 2014-01-01 till 2016-12-31

  Our current dependence on fossil fuels as the primary energy source and carrier must eventually be superseded by a new energy-matrix that is secure, renewable and environmentally friendly. The development ...

• Current trends in multifunctional Dirac materials, an international workshop

  Forskningsprojekt från 2016-11-01 till 2016-11-30

  Name of the conference: Current Trends in Multifunctional Dirac Materials, an International Workshop. In Swedish: Aktuella trender i  multifunktionella Dirac materialer, en internationel workshop.The ...

• An Experimental View on the Molecular Phase Space

  Forskningsprojekt från 2018-01-01 till 2021-12-31

  Amyloid fibers are associated with more than \num{20} human diseasesranging from diabetes to Alzheimer´s. Still, the initiation of fiberformation has eluded scientists because of the many rapidconformational ...

• Analys av enskilda celler för precisionsmedicin vid akut barnleukemi

  Forskningsprojekt från 2020-01-01 till 2023-12-31

  The established chemotherapeutic treatment strategies used in pediatric oncology benefit groups of patients with similar clinical manifestations. Relapsed, chemorefractory, and extramedullary disease remain ...

• Antimicrobial Peptides Against Crops Disease

  Forskningsprojekt från 2017-01-01 till 2018-12-31

  With an ever-increasing world population, the challenge remains to increase crop production in a sustainable way, so as not to exhaust the land of its potency for future uses. In this context, plant disease ...

• Användande av naturliga produkter för att förbättra vattenrening och jordsanering

  Forskningsprojekt från 2012-01-01 till 2014-12-31

  A key requirement for society is clean water for drinking, washing and other domestic purposes. This provision is coupled to the need to protect the environment from pollution. In many countries, the cost ...

• Användningen av självprovtagning och repeterat HPV test i den gynekologiska hälsokontrollen för att reducera förekomsten av livmoderhalscancer: en randomiserad studie

  Forskningsprojekt från 2014-01-01 till 2015-12-31

  Cervical cancer is the second most frequent cancer in women and caused by persistent infection by human papillomavirus (HPV). The organised screening in Sweden has reduced the incidence of cervical cancer ...

• Arrested infektion: sonderings steg i viralt inträde med artificiella membran

  Forskningsprojekt från 2018-01-01 till 2021-12-31

  Enveloped viruses such as influenza, HIV, and Zika enter cells via a process of membrane fusion between the viral envelope and a cellular membrane, mediated by viral fusion proteins.  The non-protein components ...

• Astrocyter i subpiala zonen som ursprung till gliom i hjärnbarken

  Forskningsprojekt från 2015-01-01 till 2017-06-30

  Astrocytes, the most abundant cell population in the brain, show temporal and regional heterogeneity. Astrocytomas, the most common primary malignant brain tumor in adult patients, are often localized ...

• Att avslöja den biologiska vattenspjälkningsmekanismen

  Forskningsprojekt från 2020-12-01 till 2024-11-30

  Photosynthetic water oxidation is the basis of higher life on Earth. The electrons and protons required for CO2 fixation are extracted by photosystem II (PSII) in a light-driven process from water. This ...

• Autonom fenotypisk läkemedelsprofilering

  Forskningsprojekt från 2020-12-01 till 2024-11-30

  The experimental space of biomedical research is vast and in many cases infeasible to cover with conventional methods where experiments are selected and carried out by humans. The purpose of this project ...

• Ribosomens basala mekanismer

  Forskningsprojekt från 2016-01-01 till 2018-12-31

  We propose to study the structure-function relations of the bacterial ribosome. The ribosome is a large (2.5 MD) macromolecular complex that makes peptide chains with amino acid sequences as prescribed ...

• Beräkningar för strukturell masspektrometri

  Forskningsprojekt från 2016-01-01 till 2018-12-31

  The structure and dynamics of biomolecules are intimately coupled to biological function, and numerous diseases are rooted in biomolecular structure. Functionally important conformational states are often ...

• Beräkningsmodellering och funktionell valideringsplattform för individanpassad kolorektalcancer stöd vid klinisk terapibeslut.

  Forskningsprojekt från 2021-01-01 till 2023-12-31

  More than 150.000 persons within EU- die of colorectal cancer every year (more than 10% cancer-related deaths). For advanced-stages, where surgery is not possible, systemic therapy is used. Although new ...

• Bestämmande faktorer för effektiv syntes, veckning och målinriktning av proteiner i levande celler

  Forskningsprojekt från 2020-01-01 till 2023-12-31

  Protein synthesis has been studied for decades, and we have a detailed picture of the process in vitro. However, when researchers aim to exploit the system, e.g. for recombinant protein production, or ...

• Bestämning av reaktionsmekanism och specificitet vid igenkänning av nukleotidsekvenser

  Forskningsprojekt från 2021-01-01 till 2023-12-31

  In this project we will address the fundamental question of how the genetic information in DNA codes for rates of binding and unbinding, by using p53 - DNA binding as a model system. To answer this question ...

• Betydelsen av fettsyror för ektopisk fettinlagring och muskelhypertrofi: metabola och molekylära studier

  Forskningsprojekt från 2015-01-01 till 2017-12-31

  Factors influencing body fat accumulation are poorly understood. Individuals that deposit fat in the liver, muscle and pancreas (ectopic fat) without increasing lean tissue (sarcopenic obesity) are prone ...

• Bortom Gleason gradering - Malignitetsgradering av prostate cancer med bildanalys teknik

  Forskningsprojekt från 2013-01-01 till 2014-12-31

  Prostate cancer is the leading cause of death in men. The diagnosis and prognosis is based on Gleason grading which is the most widely used system for determining the severity of prostate cancer from tissue ...

• Bildanalys för pålitlig och kostnadseffektiv cancerdetektion

  Forskningsprojekt från 2016-01-01 till 2018-12-31

  A crucial aspect for reliable automated analysis of cell samples for cancer detection is accurate and robust quantification of very subtle changes in the nuclear chromatin distribution through image analysis ...

• Biobank Sverige

  Forskningsprojekt från 2020-01-01 till 2024-12-31

  The scientific goal of Biobank Sweden (BIS) is to provide efficient, coordinated and sustainable use of biobank samples and associated healthcare and molecular analysis data as the basis for internationally ...

• Biobank Sverige

  Forskningsprojekt från 2018-01-01 till 2019-12-31

  The scientific goal of Biobank Sweden (BIS) is to provide efficient, coordinated and sustainable use of biobank samples and associated healthcare and molecular analysis data as the basis for internationally ...

• Intracellulär Biofysik

  Forskningsprojekt från 2013-01-01 till 2018-12-31

  The overall ambition is to make intracellular measurements that bridge the gap between quantitative physical models and biological observations in order to identify and resolve inconsistencies in our current ...

Visar 30 av 178 träffar