Forskning vid Uppsala universitet

Forskningsprojekt från 2015-07-01 till 2015-07-31

Preconception Health and Care International Conference, Uppsala 2016-02-17, 18 and 19Preconception care is defined as a set of interventions that aim to identify and modify biomedical behavioural and ...

Forskningsprojekt från 2012-01-01 till 2012-12-31

This conference explores how the molecules of life link to the phenotype of the organism. In particular, we focus on the frontiers of the three interconnected topics: developmental biology, neurobiology ...

Forskningsprojekt från 2018-11-26 till 2019-08-31

Syfte och mål: Projektet syftar till att möjliggöra att biobanker och hälsodata på ett effektivt och säkert sätt kan kombineras och användas enligt patientens samtycke för akademisk och industriell forskning ...

Forskningsprojekt från 2015-11-01 till 2015-11-30

Conference name and location: Advancing the Frontiers of (Bio)Chemistry with Valence Bond Approaches. Uppsala University, Sweden.Time for the conference (year-month-day): 2016/06/22-24Justification of ...

Forskningsprojekt från 2012-01-01 till 2014-12-31

Fibrillar alpha-synuclein in Lewy bodies is the main hallmark in brains of patients with Parkinson´s disease and some other brain disorders. However, recent studies indicate that oligomers or protofibrils ...

Forskningsprojekt från 2012-01-01 till 2014-12-31

Computer simulation is a tool for better understanding of the reactions between molecules and their diffusion in living cells. There are now experimental data for single molecules to compare with and for ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

Generation of architectural polarity impacts all cell types, ranging from epithelial cells to neurons and astrocytes, relates to tissue organization and links to disease development when misregulated. ...

Forskningsprojekt från 2020-08-01 till 2020-12-31

Low molecular-weight heparin (LMWH) has rapidly become a primary drug in treatment of Covid-19 patients. A major rationale is the pulmonary coagulopathy typical of the seriously ill patient. Increasing ...

Forskningsprojekt från 2016-01-01 till 2018-12-31

We propose to study the structure-function relations of the bacterial ribosome. The ribosome is a large (2.5 MD) macromolecular complex that makes peptide chains with amino acid sequences as prescribed ...

Forskningsprojekt från 2013-01-01 till 2015-12-31

The ribosome is a large macromolecular complex of two subunits. It links amino acids into proteins according to the messenger RNA (mRNA) instructions. The twenty amino acids (aa) are covalently coupled ...

Forskningsprojekt från 2012-01-01 till 2014-12-31

Ginseng polysaccharide is a complex mixture of neutral and acidic polysaccharides that has been proven to have anticancer activities. It functions through interactions with a protein called Galectin-3. ...

Forskningsprojekt från 2020-01-01 till 2023-12-31

Protein synthesis has been studied for decades, and we have a detailed picture of the process in vitro. However, when researchers aim to exploit the system, e.g. for recombinant protein production, or ...

Forskningsprojekt från 2015-01-01 till 2015-12-31

I have previously identified over 40 novel genes that code for new members of the solute carrier family and many of these are likely to be novel transporters for amino acids. A number of these were evolutionary ...

Forskningsprojekt från 2013-01-01 till 2018-12-31

The overall ambition is to make intracellular measurements that bridge the gap between quantitative physical models and biological observations in order to identify and resolve inconsistencies in our current ...

Forskningsprojekt från 2012-01-01 till 2014-12-31

The aim is to study the structure and function of the CO2-concentration machinery in phytoplankton. Competition between O2 and CO2 at the active site of the CO2-fixing enzyme, Rubisco, reduces the efficiency ...

Forskningsprojekt från 2011-01-01 till 2015-12-31

A grand challenge for the 21st century is to develop a molecular-level understanding of a living cell. A key step in this direction is to obtain structures for individual cell organelles. The structure ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

This project deals with computational studies in the general areas of biological catalysis and molecular recognition. We emphasize what may be called quantitative computational structural biology, where ...

Forskningsprojekt från 2019-01-01 till 2022-12-31

This project deals with the problem of how enzymes can be shaped by evolution to work under extreme conditions. In particular, we will address cold-adapted enzymes that are able to maintain a high catalytic ...

Forskningsprojekt från 2014-01-01 till 2017-12-31

This project is focused on understanding GPCR dimerization and strategies to discover ligands of receptors using structure-based methods. The A2A adenosine (A2AAR) and D2 dopamine (D2DR) receptors form ...

Forskningsprojekt från 2012-01-01 till 2015-12-31

Life processes depend critically on interactions between macromolecules. Many of these interactions involve coupled folding and binding, which lies at the heart of many biologically, medically, and technologically ...

Forskningsprojekt från 2021-01-01 till 2024-12-31

Phosphorylation and ubiquitination are among the most common post-translational modifications (PTMs) and regulate together most cellular processes. The PTMs are catalyzed by more than 500 kinases and 600 ...

Forskningsprojekt från 2013-09-01 till 2014-08-31

Syfte och mål: Projektets har uppfyllt sitt mål är att skapa och sprida kunskap kring införande och användning av patientjournal på nätet och andra e-hälsotjänster. Projektet har även uppfyllt sina syften ...

Forskningsprojekt från 2012-06-01 till 2014-08-31

Syfte och mål: Projektets har uppfyllt sitt mål är att skapa och sprida kunskap kring införande och användning av patientjournal på nätet och andra e-hälsotjänster. Projektet har även uppfyllt sina syften ...

Forskningsprojekt från 2014-01-01 till 2017-12-31

Emotional evaluation of daily environmental and internal stimuli is essential for proper guidance of motivated and goal-directed behaviour. Central in this process is the ventral tegmental area (VTA) with ...

Forskningsprojekt från 2015-01-01 till 2017-12-31

Toxicology testing is one of the main reasons for use of experimental animals. We set up a productive fly (Drosophila) lab, with a range of methodologies, enabling detailed molecular, physiological and ...

Forskningsprojekt från 2013-01-01 till 2016-12-31

The establishment of the musculoskeletal system of the head was tremendously important for the evolutionary transition from jawless to jawed vertebrates. The arrangement of cartilage, dermal bones, and ...

Forskningsprojekt från 2013-01-01 till 2015-12-31

Over the past few years, new sequencing technologies have led to the discovery of novel types of RNA and novel catalytic functions for RNA in the cell. RNA-sequencing has further increased the ability ...

Forskningsprojekt från 2015-01-01 till 2018-12-31

The purpose is to develop, test, and evaluate the clinical efficacy and cost-effectiveness of an online cognitive behavioral-based intervention for psychological distress for parents of children previously ...

Forskningsprojekt från 2012-01-01 till 2013-12-31

The SNP&SEQ technology platform offers high-quality genotyping services on a wide size range, from individual SNP markers to genome-wide genotyping with 2.5 million SNPs to academic researchers in Sweden ...

Forskningsprojekt från 2014-01-01 till 2015-12-31

The SNP&SEQ technology platform has offered high-quality genotyping services on a wide size range, from individual SNP markers to genome-wide genotyping to academic researchers since 2001. In 2008, second ...