Research at Uppsala University

• A community-based participatory intervention to change attitudes towards female circumcision among Somali immigrants in Sweden: a cluster-randomised controlled trial

  Research project from 2016-01-01 to 2018-12-31

  Due to the harmful consequences of female circumcision (FC), this project will seek to decrease the support of its continuation among newly arrived Somalis in Sweden. The hypothesis is that a community-based ...

• Aiming at prolonging the therapeutic lifespan of artemisinin-based combination therapies in an era of imminent Plasmodium falciparum resistance in East-Africa - new strategies with old tools

  Research project from 2017-01-01 to 2019-12-31

  Global malaria control is under threat due to evolution and spread of P. falciparum resistance to artemisinin-based combination therapies (ACTs) in Southeast Asia. Artemisinin resistance is phenotypically ...

• An intervention to change attitudes towards female circumcision among the Somali-Swedish community: a cluster-randomised controlled trial

  Research project from 2016-01-01 to 2018-12-31

  Due to the harmful consequences of female circumcision (FC), this project will seek to decrease the support of its continuation among newly arrived Somalis in Sweden. The hypothesis is that a community-based ...

• Computations for structural mass spectrometry

  Research project from 2016-01-01 to 2018-12-31

  The structure and dynamics of biomolecules are intimately coupled to biological function, and numerous diseases are rooted in biomolecular structure. Functionally important conformational states are often ...

• Biodiversity and chemodiversity of Sri Lankan marine sponges: an opportunity to explore new pharmaceutical applications

  Research project from 2018-01-01 to 2020-12-31

  Sponges (phylum Porifera) are unquestionably the most promising source of new marine compounds and yet, they are quite often neglected in the field of natural products research because of the extreme difficulty ...

• Central Sweden Cohorts & Biobank

  Research project from 2018-01-01 to 2022-12-31

  Building of the Central Swedish Cohorts & Biobank infrastructure started 30 years ago and includes 110,000 women and men born between 1914-1952, living in the counties of Uppsala, Västmanland and Örebro ...

• Metropolitan mosquitoes: Understanding urban livestock keeping and vector-borne disease in growing tropical cities - the potential of sustainable control methods and the risks for emergence to Sweden.

  Research project from 2016-01-01 to 2020-12-31

  With more than 50% of the global population living in urban areas, cities are not only crowded with humans, but also with the livestock brought there to provide for high value animal-source food products ...

• The socioeconomic gradient in child health through childhood and across time

  Research project from 2016-01-01 to 2018-12-30

  There is strong persistence in social status across generations. Parental socioeconomic status may affect child health through channels such as parent’s income, education level, health and relative social ...

• Development and characterisation of novel ADCs

  Research project from 2015-01-01 to 2019-12-31

  The development and characterisation of antibody-drug-conjugates (ADCs) are the heart of this application. Our project focuses on a very new class of acid labile linkers for ADCs. Recent progress in anti-cancer ...

• Development of Tailored Microanalytical Tools for Neuroscience

  Research project from 2016-01-01 to 2019-12-31

  This research project represents novel analytical possibilities in the translational field between analytical chemistry and neurochemistry, including fundamental aspects of sample preparation, multidimensional ...

• Development of a diamond waveguide sensor for ultra sensitive chemical analysis using tunable mid-IR quantum cascade lasers

  Research project from 2015-01-01 to 2018-12-31

  The project is aimed to develop a sensitive chemical sensor based on a microfabricated diamond waveguide. By coupling mid-IR light into a macroscopic diamond crystal FTIR-ATR spectroscopy can be performed ...

• Development of methods for probing ligand-receptor interactions in situ using frontal affinity chromatography coupled with desorption electrospray ionization mass spectrometry

  Research project from 2015-07-01 to 2018-06-30

  The association of seven transmembrane helices with the lipid bilayer of a biological cell is both what structurally defines G-protein coupled receptors (GPCR), and what makes them very difficult to study ...

• Developmental Origins of Health and Disease: Effects of pregnancy nutrition interventions on growth, body composition and timing of puberty. Follow-up of the MINIMat trial in rural Bangladesh.

  Research project from 2016-01-01 to 2018-12-31

  This is a follow-up of the MINIMat trial in rural Bangladesh that was implemented in a setting, where food insecurity and maternal malnutrition still prevail, but where changing lifestyles and economic ...

• Developmental Origins of Health and Disease: Effects of prenatal nutrition interventions on physical activity and metabolic risk indicators adolescents: A 15 y follow-up of MINIMat trial in Bangladesh

  Research project from 2017-01-01 to 2019-12-31

  There are well-documented associations between early life nutrition and long-term health. The epidemic of chronic diseases in low- and middle-income countries including Bangladesh affects societies where ...

• Developmental origins of health and disease. Prenatal exposure to iron and environmental toxicants and associations with neurodevelopment and metabolic risk indicators at 15 years in rural Bangladesh

  Research project from 2018-01-01 to 2020-12-31

  Studies indicated that iron overload or exposure to environmental pollutants such as, polycyclic aromatic hydrocarbons (PAHs) in early life is associated with disease patterns later in life. Exposure to ...

• The EXPRESS study. Follow-up at 11 years of extremely preterm infants in Sweden.

  Research project from 2015-01-01 to 2018-12-31

  Progress in perinatal care has resulted in an increase in the survival of extremely preterm infants creating a new population with an increased risk for later disabilities. Our study population comprise ...

• Early life exposures: the microbiome and type 1 diabetes

  Research project from 2016-01-01 to 2019-12-31

  The incidence of type 1 diabetes has doubled in the last 30 years in Sweden, most likely because of a concomitant increase in one or several as yet unidentified environmental causes. The “hygiene hypothesis ...

• Evaluation of a group intervention for post traumatic stress in refugee adolescents - a randomised trial

  Research project from 2017-12-01 to 2018-12-31

  A total of 18 294 youth aged 16-17 years are waiting for their asylum decisions; most are unaccompanied refugee minors (URM). Post-Traumatic Stress Disorder (PTSD) is prevalent in this group; 76% of the ...

• Functional molecular and polymeric compounds for high-energy battery cathodes

  Research project from 2017-01-01 to 2020-12-31

  Li-based batteries outperform all other rechargeable technologies in terms of energy density, but the limited efficiency and life-time of next-generation battery materials impede their further implementation ...

• Future Leaders Program of STS Forum

  Research project from 2018-09-03 to 2018-11-14

  Purpose and goal: The purpose of the conference was to enable young scientists to network and discuss common visions and obstacles to overcome in today´s society. Expected results and effects: By ...

• High throughput metabolite profiling of living single cells - application to stroke pathology

  Research project from 2018-01-01 to 2021-12-31

  Single cells analysis currently attracts a lot of attention since it can significantly advance our understanding of cell function and cellular processes of importance to health and disease. In particular ...

• Markers of Imminent Myocardial Infarction (MIMI)

  Research project from 2017-01-01 to 2019-12-31

  Myocardial infarction is the leading cause of death globally, and increasing. The high-risk primary prevention strategies of today have low precision and limited adherence by patients and doctors. We hypothesize ...

• Sustainable use of antivirals in seasonal influenza and pandemic preparedness – ranking risk of environmental resistance development and understanding resistance transmission towards humans​

  Research project from 2017-01-01 to 2019-12-31

  Influenza is a major public health threat and anti-influenza drugs are crucial for treatment and prophylaxis, especially early in a pandemic, before vaccines can be mass-produced. However, antiviral drugs ...

• Language impairment or typical language development? Developing methods for linguistic assessment of bilingual children in Sweden

  Research project from 2014-01-01 to 2018-12-31

  Many children in Sweden grow up in a multilingual setting. Some of these children are slow in their language development and are referred to a speech-language pathologist (SLP) for assessment and intervention ...

• Outdoor air pollution and indoor environment in homes and school in China: effects on asthma, rhinitis, dermatitis and respiratory health in preschool children and students

  Research project from 2018-01-01 to 2020-12-31

  The overall aim is to study health effects of outdoor air pollution, climate and indoor environment (homes, schools) across China on asthma, rhinitis, dermatitis and respiratory health in Chinese children ...

• Mother anyway: Literary, Medical and Media Narratives

  Research project from 2017-01-01 to 2019-12-31

  What does motherhood mean today in a society with an advanced but negotiated welfare system? The question is intimately related to notions of gender equality and welfare regimes, and the aim of the project ...

• Man’s best friend: A crossborder transdisciplinary One Health approach to rabies control in dogs in Southeast Asia

  Research project from 2018-01-01 to 2020-12-31

  Rabies is estimated to kill more than 30,000 people every year in Asia. Most cases are caused by dog bites, and deaths most commonly occur among the poorest or the most remote population, unable to receive ...

• Mentoring as a method to promote women´s health and empowering women in the context of HIV-prevention and unequal gender relations

  Research project from 2017-10-01 to 2019-09-30

  This project has a double aim: 1. To investigate the approach to managing women’s health and rehabilitation including HIV treatment by such South African NGOs as mothers2mothers (m2m), Yabonga, and Philani ...

• Migration and equity in sexual and reproductive health: The importance of dynamics in cultural and social values for improving practice through co-production

  Research project from 2018-12-01 to 2024-12-31

  Sweden is a multicultural country. Many migrants from the Middle East (ME) and Somalia have cultural values that contrast sharply with liberal values in Sweden. Sexual and reproductive health (SRH) is ...

• Next generation isotope analysis in field research

  Research project from 2017-01-01 to 2019-12-31

  The project will investigate new technology and methodology for the next generation of isotope ratio measurements in the field of environmental science, with special focus on greenhouse gas (GHG) evasion ...

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